SCHEMBL6861318

SCHEMBL6861318

C=CCCCCCC[SiH2]CC

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.54
ALDH1A1 P00352 3/20 0.46
ABCC4 O15439 1/20 0.37
MAPT P10636 1/20 0.37
LMNA P02545 1/20 0.36
TRPA1 O75762 2/20 0.34
LPAR3 Q9UBY5 2/20 0.32
LPAR2 Q9HBW0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6861926 0.84 TSHR (0.73) TSHRALDH1A1ABCC4MAPTLMNA
SCHEMBL3366893 0.78 TSHR (0.44) TSHRALDH1A1ABCC4MAPTLMNA
SCHEMBL3361113 0.78 TSHR (0.44) TSHRALDH1A1ABCC4MAPTLMNA
SCHEMBL17242077 0.75 TSHR (0.52) TSHRALDH1A1ABCC4MAPTLMNA
SCHEMBL28174666 0.75 TSHR (0.52) TSHRALDH1A1ABCC4MAPTLMNA
SCHEMBL9486873 0.75 TSHR (0.52) TSHRALDH1A1ABCC4MAPTLMNA
SCHEMBL10772647 0.72 TSHR (0.69) TSHRALDH1A1ABCC4MAPTLMNA
SCHEMBL18187342 0.72 TSHR (0.69) TSHRALDH1A1ABCC4MAPTLMNA
SCHEMBL2846645 0.72 TSHR (0.69) TSHRALDH1A1ABCC4MAPTLMNA
SCHEMBL18187344 0.72 TSHR (0.69) TSHRALDH1A1ABCC4MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1204149-C Improved olefin polymerization process DOW CHEMICAL CO (US) 2005-06-01 CN disclosed
EP-1054910-B1 IMPROVED OLEFIN POLYMERIZATION PROCESS DOW GLOBAL TECHNOLOGIES INC (US) 2004-09-22 EP disclosed
US-6258902-B1 USING A METAL COMPLEX CATALYST AND AN ALKENYL CONTAINING HYDROCARBYLSILANE THE DOW CHEMICAL COMPANY 2001-07-10 US disclosed
CN-1289343-A Improved olefin polymerization process DOW CHEMICAL CO (US) 2001-03-28 CN disclosed
EP-1054910-A1 IMPROVED OLEFIN POLYMERIZATION PROCESS THE DOW CHEMICAL COMPANY (US) 2000-11-29 EP disclosed
WO-1999041289-A1 IMPROVED OLEFIN POLYMERIZATION PROCESS THE DOW CHEMICAL COMPANY (US) 1999-08-19 WO disclosed