Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RARB | P10826 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8506187 | 0.99 | NR5A1 (0.51) | NR5A1KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL8505255 | 0.90 | NR5A1 (0.44) | NR5A1KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL9138896 | 0.85 | KDM4E (0.53) | NR5A1KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL9140257 | 0.85 | KDM4E (0.53) | NR5A1KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL6863382 | 0.85 | KDM4E (0.53) | NR5A1KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL8506313 | 0.85 | KDM4E (0.53) | NR5A1KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL8506175 | 0.84 | KDM4E (0.50) | NR5A1KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL8504280 | 0.84 | KDM4E (0.52) | NR5A1KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL7110595 | 0.83 | KDM4E (0.51) | NR5A1KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL6863866 | 0.83 | KDM4E (0.51) | NR5A1KDM4EALDH1A1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0930301-B1 | 2-Fluoropyridine, process for producing it and its use in liquid crystal mixtures | AVENTIS RES & TECH GMBH & CO (DE) | 2004-07-28 | — | — | EP | disclosed |
| EP-0513262-B1 | 3,6-DISUBSTITUTED 2-FLUOROPYRIDINES | MERCK PATENT GMBH (DE) | 2000-04-05 | — | — | EP | disclosed |
| EP-0563146-B1 | 2-FLUOROPYRIDINE, PROCESS FOR PRODUCING IT AND ITS USE IN LIQUID CRYSTAL MIXTURES | HOECHST AG (DE) | 1999-10-06 | — | — | EP | disclosed |
| EP-0930301-A1 | 2-Fluoropyridine, process for producing it and its use in liquid crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-07-21 | — | — | EP | disclosed |
| US-5630962-A | 2-Fluoropyridines, their preparation and their use in liquid crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-20 | — | — | US | disclosed |
| US-5389291-A | Components of liquid crystalline media | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-02-14 | — | — | US | disclosed |
| EP-0563146-A1 | 2-FLUOROPYRIDINE, PROCESS FOR PRODUCING IT AND ITS USE IN LIQUID CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-10-06 | — | — | EP | disclosed |
| EP-0513262-A1 | 3,6-DISUBSTITUTED 2-HALOPYRIDINES | MERCK PATENT GmbH (DE) | 1992-11-19 | — | — | EP | disclosed |
| WO-1992011241-A1 | 2-FLUOROPYRIDINE, PROCESS FOR PRODUCING IT AND ITS USE IN LIQUID CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-07-09 | — | — | WO | disclosed |
| WO-1992009576-A1 | 3,6-DISUBSTITUTED 2-HALOPYRIDINES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1992-06-11 | — | — | WO | disclosed |