Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 3/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6861378 | 0.90 | NR5A1 (0.53) | NR5A1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL8506187 | 0.89 | NR5A1 (0.51) | NR5A1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL8506788 | 0.86 | KDM4E (0.43) | NR5A1PTPN11KDM4EALDH1A1HPGD | |
| SCHEMBL8504621 | 0.80 | TSHR (0.46) | PTPN11KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9698503 | 0.79 | MCL1 (0.50) | NR5A1MCL1PTPN11CNR2THRA | |
| SCHEMBL9181458 | 0.77 | KDM4E (0.52) | NR5A1MCL1PTPN11KDM4EALDH1A1 | |
| SCHEMBL9140257 | 0.76 | KDM4E (0.53) | NR5A1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL9138896 | 0.76 | KDM4E (0.53) | NR5A1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL8506313 | 0.76 | KDM4E (0.53) | NR5A1PTPN11KDM4EALDH1A1HPGD | |
| SCHEMBL6863382 | 0.76 | KDM4E (0.53) | NR5A1KDM4EALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563146-B1 | 2-FLUOROPYRIDINE, PROCESS FOR PRODUCING IT AND ITS USE IN LIQUID CRYSTAL MIXTURES | HOECHST AG (DE) | 1999-10-06 | — | — | EP | disclosed |
| EP-0930301-A1 | 2-Fluoropyridine, process for producing it and its use in liquid crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-07-21 | — | — | EP | disclosed |
| US-5630962-A | 2-Fluoropyridines, their preparation and their use in liquid crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-20 | — | — | US | disclosed |
| EP-0563146-A1 | 2-FLUOROPYRIDINE, PROCESS FOR PRODUCING IT AND ITS USE IN LIQUID CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-10-06 | — | — | EP | disclosed |
| WO-1992011241-A1 | 2-FLUOROPYRIDINE, PROCESS FOR PRODUCING IT AND ITS USE IN LIQUID CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-07-09 | — | — | WO | disclosed |