Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.72 |
| ▸ | MAOA | P21397 | 3/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.72 |
| ▸ | SDHA | P31040 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | CALML3 | P27482 | 1/20 | 0.72 |
| ▸ | F10 | P00742 | 9/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859879 | 1.00 | MAOB (0.72) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL8590924 | 0.92 | MAOA (0.61) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL6755402 | 0.91 | MAOA (0.60) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL6865295 | 0.91 | MAOB (0.68) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL6753194 | 0.90 | MAOA (0.59) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL6755502 | 0.89 | MAOA (0.58) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL6755399 | 0.88 | MAOB (0.79) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL6755396 | 0.88 | MAOB (0.79) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL5431183 | 0.88 | MAOB (0.75) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL27801854 | 0.88 | MAOB (0.75) | MAOBMAOAPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3558088-B2 | — | — | 2004-08-25 | — | — | JP | claimed |
| EP-0673370-B1 | TROPONE-SUBSTITUTED PHENYLOXAZOLIDINONE ANTIBACTERIAL AGENTS | UPJOHN CO (US) | 1998-01-07 | — | — | EP | claimed |
| EP-0673370-A1 | TROPONE-SUBSTITUTED PHENYLOXAZOLIDINONE ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1995-09-27 | — | — | EP | claimed |
| WO-1994013649-A1 | TROPONE-SUBSTITUTED PHENYLOXAZOLIDINONE ANTIBACTERIAL AGENTS | THE UPJOHN COMPANY (US) | 1994-06-23 | — | — | WO | claimed |
| EP-0673370-B1 | TROPONE-SUBSTITUTED PHENYLOXAZOLIDINONE ANTIBACTERIAL AGENTS | UPJOHN CO (US) | 1998-01-07 | — | — | EP | disclosed |
| US-5523403-A | Tropone-substituted phenyloxazolidinone antibacterial agents | THE UPJOHN COMPANY (US) | 1996-06-04 | — | — | US | disclosed |
| EP-0673370-A1 | TROPONE-SUBSTITUTED PHENYLOXAZOLIDINONE ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1995-09-27 | — | — | EP | disclosed |
| WO-1994013649-A1 | TROPONE-SUBSTITUTED PHENYLOXAZOLIDINONE ANTIBACTERIAL AGENTS | THE UPJOHN COMPANY (US) | 1994-06-23 | — | — | WO | disclosed |