Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1273861 | 1.00 | ALDH1A1 (0.59) | ALDH1A1TSHRTHRBCES2CES1 | |
| SCHEMBL1246392 | 1.00 | ALDH1A1 (0.59) | ALDH1A1TSHRTHRBCES2CES1 | |
| SCHEMBL1965259 | 1.00 | — | — | |
| SCHEMBL5615699 | 1.00 | ALDH1A1 (0.59) | ALDH1A1TSHRTHRBCES2CES1 | |
| SCHEMBL505895 | 0.97 | — | — | |
| SCHEMBL4880978 | 0.88 | — | — | |
| SCHEMBL2887420 | 0.79 | TSHR (0.50) | ALDH1A1TSHRTHRBDNM1LMNA | |
| SCHEMBL1117388 | 0.74 | ALDH1A1 (1.00) | ALDH1A1TSHRTHRBCES2CES1 | |
| SCHEMBL1117329 | 0.74 | ALDH1A1 (1.00) | ALDH1A1TSHRTHRBCES2CES1 | |
| SCHEMBL30906963 | 0.74 | ALDH1A1 (1.00) | ALDH1A1TSHRTHRBCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6835754-B2 | Administering alpha-(4-hydroxy-3,5-di-tert-butylphenyl)-N-tert-octylnitrone for example | RENOVIS, INC. | 2004-12-28 | — | — | US | disclosed |