Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 16/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 14/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14068919 | 0.87 | SLC6A3 (0.76) | SLC6A3SLC6A2SLC6A4RAB9AALDH1A1 | |
| SCHEMBL27513426 | 0.86 | SLC6A2 (0.50) | SLC6A3SLC6A2SLC6A4RAB9AALDH1A1 | |
| SCHEMBL17645635 | 0.83 | SLC6A3 (0.68) | SLC6A3SLC6A2SLC6A4RAB9AHSP90AA1 | |
| SCHEMBL11665417 | 0.82 | SLC6A3 (0.75) | SLC6A3SLC6A2SLC6A4RAB9AALDH1A1 | |
| SCHEMBL4939421 | 0.80 | SLC6A3 (0.77) | SLC6A3SLC6A2SLC6A4RAB9AHSP90AA1 | |
| SCHEMBL9037624 | 0.80 | SLC6A3 (0.68) | SLC6A3SLC6A2SLC6A4RAB9AALDH1A1 | |
| SCHEMBL27563959 | 0.79 | SLC6A3 (0.66) | SLC6A3SLC6A2SLC6A4RAB9AALDH1A1 | |
| SCHEMBL4936204 | 0.78 | SLC6A3 (1.00) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL27098438 | 0.77 | SLC6A3 (0.81) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL27098434 | 0.77 | SLC6A3 (0.81) | SLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999204-B1 | NOVEL COMPOUND HAVING EFFECT OF PROMOTING NEURON DIFFERENTIATION | NIPPON KAYAKU KK (JP) | 2004-10-13 | — | — | EP | disclosed |
| CN-1268937-A | Novel compound having effect of promoting neuron differentiation | NIPPON KAYAKU KK (JP) | 2000-10-04 | — | — | CN | disclosed |