Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 7/20 | 0.46 |
| ▸ | RXRB | P28702 | 6/20 | 0.46 |
| ▸ | RXRG | P48443 | 6/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1138812 | 0.94 | TRPV1 (0.40) | RXRARXRBRXRGERAP1ERAP2 | |
| SCHEMBL6861324 | 0.90 | RXRA (0.50) | RXRARXRBRXRGERAP1ERAP2 | |
| SCHEMBL6864186 | 0.89 | RXRA (0.48) | RXRARXRBRXRGERAP1ERAP2 | |
| SCHEMBL1140185 | 0.89 | RXRA (0.51) | RXRARXRBRXRGERAP1ERAP2 | |
| SCHEMBL6861346 | 0.88 | RXRA (0.52) | RXRARXRBRXRGERAP1ERAP2 | |
| SCHEMBL6864123 | 0.88 | RXRA (0.48) | RXRARXRBRXRGERAP1ERAP2 | |
| SCHEMBL6855975 | 0.87 | RXRA (0.47) | RXRARXRBRXRGERAP1ERAP2 | |
| SCHEMBL1138906 | 0.87 | TRPV1 (0.38) | RXRARXRBRXRGERAP1ERAP2 | |
| SCHEMBL6861611 | 0.87 | RXRA (0.50) | RXRARXRBRXRGERAP1ERAP2 | |
| SCHEMBL1139197 | 0.86 | RXRA (0.49) | RXRARXRBRXRGERAP1ERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6790866-B2 | SUCH AS 4-(2-PHENYLSULFONYLAMINO-5-CHLOROBENZOYLAMINO)BENZOIC ACID FOR USE AS PROSTAGLANDIN E2 ANTAGONIST OR AGONIST; FOR INHIBITION OF UTERINE CONTRACTION, ANALGESICS, ANTIDIARRHEALS, SLEEP INDUCERS, AND/OR FOR INCREASE OF VESICAL CAPACITY | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-09-14 | — | — | US | disclosed |