Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6862646 | 1.00 | HRH3 (0.43) | HRH3KCNH2ALDH1A1PIM1KDM4E | |
| SCHEMBL6862651 | 1.00 | HRH3 (0.43) | HRH3KCNH2ALDH1A1PIM1KDM4E | |
| SCHEMBL4597254 | 0.81 | AR (0.38) | ALDH1A1PIM1 | |
| SCHEMBL3568982 | 0.81 | AR (0.38) | ALDH1A1PIM1 | |
| SCHEMBL4597253 | 0.81 | AR (0.38) | ALDH1A1PIM1 | |
| SCHEMBL12916351 | 0.80 | PIM1 (0.39) | ALDH1A1PIM1POLBHTR2AHTR2C | |
| SCHEMBL13808671 | 0.80 | PIM1 (0.39) | ALDH1A1PIM1POLBHTR2AHTR2C | |
| SCHEMBL22542012 | 0.80 | PIM1 (0.39) | ALDH1A1PIM1POLBHTR2AHTR2C | |
| SCHEMBL24028089 | 0.79 | PIM1 (0.38) | ALDH1A1PIM1KDM4EHTR2AHTR2C | |
| SCHEMBL4935360 | 0.79 | PIM1 (0.44) | HRH3PIM1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040010037-A1 | Cyanophenyl derivative | YAMANOUCHI PHARMACEUTICAL CO., LTD. | 2004-01-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040010037-A1 | Cyanophenyl derivative | BPHL, AR, KLK3 | HRH3 3229/4885KCNH2 3221/4885ALDH1A1 1496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.