Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19121486 | 0.83 | HDAC4 (0.46) | HDAC4HDAC2HDAC8TSHRKDM4E | |
| SCHEMBL11954263 | 0.83 | KDM4E (0.53) | HDAC4HDAC2HDAC8TSHRKDM4E | |
| SCHEMBL19445358 | 0.81 | HDAC4 (0.45) | HDAC4HDAC2HDAC8TSHRKDM4E | |
| SCHEMBL825481 | 0.81 | HDAC4 (0.45) | HDAC4HDAC2HDAC8TSHRKDM4E | |
| SCHEMBL14119424 | 0.81 | TSHR (0.51) | HDAC4HDAC2HDAC8TSHRKDM4E | |
| SCHEMBL2632814 | 0.80 | CASR (0.51) | HDAC4HDAC2HDAC8KDM4EALDH1A1 | |
| SCHEMBL14162717 | 0.80 | CASR (0.51) | HDAC4HDAC2HDAC8KDM4EALDH1A1 | |
| SCHEMBL10192231 | 0.80 | CASR (0.51) | HDAC4HDAC2HDAC8KDM4EALDH1A1 | |
| SCHEMBL11992976 | 0.80 | CASR (0.51) | HDAC4HDAC2HDAC8KDM4EALDH1A1 | |
| SCHEMBL11999043 | 0.80 | HDAC4 (0.44) | HDAC4HDAC2HDAC8TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6709724-B1 | Metal catalyzed ascorbate compounds as oxygen scavengers | W. R. GRACE & CO.-CONN. | 2004-03-23 | — | — | US | disclosed |
| US-6656383-B1 | First polymeric carrier, catalyzing agent dispersed throughout the second concentrate, second polymeric carrier; liners or gasketing materials for crowns, closures, lids or caps of bottles or cans; packaging | W. R. GRACE & CO.-CONN. | 2003-12-02 | — | — | US | disclosed |
| EP-1077683-B1 | ANTIDEPRESSANT THERAPY | ALZA CORP (US) | 2002-12-11 | — | — | EP | disclosed |
| US-6465065-B1 | CONTAINERS HAVING WATER PERMEABLE POLYMER LININGS CONTAINING OXIDATION CATALYSTS AND SODIUM ASCORBATE FOR USE IN PACKAGING BEVERAGES, FOODS AND DRUGS | W.R. GRACE & CO.-CONN. | 2002-10-15 | — | — | US | disclosed |
| US-6391406-B1 | PACKAGING OXYGEN SENSITIVE MATERIALS SUCH AS FOODSTUFFS, BEVERAGES, AND PHARAMCEUTICALS; ASCORBIC ACID OR A SALT THEREOF DISPERSED RELATIVELY UNIFORMLY THROUGHOUT A POLYMERIC CARRIER | W. R. GRACE & CO.-CONN. | 2002-05-21 | — | — | US | disclosed |
| US-20010055614-A1 | Antidepressant therapy | SEROFF SYLVIA (US) | 2001-12-27 | — | — | US | disclosed |
| EP-1077683-A1 | ANTIDEPRESSANT THERAPY | ALZA CORPORATION (US) | 2001-02-28 | — | — | EP | disclosed |
| EP-0527207-B1 | POLYMER COMPOSITIONS CONTAINING OXYGEN SCAVENGING COMPOUNDS | GRACE W R & CO (US) | 2000-10-25 | — | — | EP | disclosed |
| EP-0664824-B1 | POLYMER COMPOSITIONS CONTAINING OXYGEN SCAVENGING COMPOUNDS | ADVANCED OXYGEN TECHNOLOGIES I (US) | 2000-01-19 | — | — | EP | disclosed |
| WO-1999058115-A1 | ANTIDEPRESSANT THERAPY | ALZA CORPORATION (US) | 1999-11-18 | — | — | WO | disclosed |
| WO-1994009084-A1 | POLYMER COMPOSITIONS CONTAINING OXYGEN SCAVENGING COMPOUNDS | ADVANCED OXYGEN TECHNOLOGIES, INC. (US) | 1994-04-28 | — | — | WO | disclosed |
| US-5246711-A | Dosage form for treating dysthymia | ALZA CORPORATION (US) | 1993-09-21 | — | — | US | disclosed |
| US-5246710-A | Dosage form for treating cyclothymia | ALZA CORPORATION (US) | 1993-09-21 | — | — | US | disclosed |
| US-5202052-A | Blends with polymeric carriers for beverage container closures or food packaging | AQUANAUTICS CORPORATION (US) | 1993-04-13 | — | — | US | disclosed |
| EP-0527207-A1 | POLYMER COMPOSITIONS CONTAINING OXYGEN SCAVENGING COMPOUNDS | ZAPATA INDUSTRIES, INC. (US) | 1993-02-17 | — | — | EP | disclosed |
| US-5185158-A | Dosage form comprising succinimide drug for treating depressive disorders and composition comprising same | ALZA CORPORATION (US) | 1993-02-09 | — | — | US | disclosed |
| WO-1991017044-A1 | POLYMER COMPOSITIONS CONTAINING OXYGEN SCAVENGING COMPOUNDS | ZAPATA INDUSTRIES, INC. (US) | 1991-11-14 | — | — | WO | disclosed |
| EP-0008131-B1 | POLY(ETHYLENE OXIDE) COMPOSITIONS | UNION CARBIDE CORPORATION (US) | 1982-12-22 | — | — | EP | disclosed |
| US-4211681-A | Poly(ethylene oxide) compositions | UNION CARBIDE CORPORATION (US) | 1980-07-08 | — | — | US | disclosed |
| EP-0008131-A1 | Poly(ethylene oxide) compositions | UNION CARBIDE CORPORATION (US) | 1980-02-20 | — | — | EP | disclosed |