Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3057391 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1L3MBTL1KDM4EAKR1C3 | |
| SCHEMBL1440018 | 0.86 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1 | |
| SCHEMBL12317391 | 0.86 | SMN1; SMN2 (0.45) | SMN1; SMN2AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL12094859 | 0.86 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1 | |
| SCHEMBL3044032 | 0.85 | SMN1; SMN2 (0.49) | SMN1; SMN2AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL8080397 | 0.85 | SMN1; SMN2 (0.49) | SMN1; SMN2AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL12317390 | 0.85 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL12317364 | 0.83 | HDAC1 (0.52) | — | |
| SCHEMBL13136808 | 0.83 | HDAC1 (0.52) | — | |
| SCHEMBL3060050 | 0.83 | HDAC1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8263044-B2 | Stilbene like compounds as novel HDAC inhibitors | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2012-09-11 | — | — | US | disclosed |
| US-8263044-B2 | Stilbene like compounds as novel HDAC inhibitors | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2012-09-11 | — | — | US | disclosed |
| WO-2007054776-A9 | STILBENE LIKE COMPOUNDS AS NOVEL HDAC INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2011-03-03 | — | — | WO | disclosed |
| US-20090136431-A1 | Stilbene Like Compounds as Novel HDAC Inhibitors | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2009-05-28 | — | — | US | disclosed |
| US-20090136431-A1 | Stilbene Like Compounds as Novel HDAC Inhibitors | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2009-05-28 | — | — | US | disclosed |
| WO-2007054776-A2 | STILBENE LIKE COMPOUNDS AS NOVEL HDAC INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090136431-A1 | Stilbene Like Compounds as Novel HDAC Inhibitors | HDAC1, HDAC5, HDAC11 | SMN1; SMN2 3628/4885ALDH1A1 205/4885L3MBTL1 3100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.