Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 19/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6867105 | 0.87 | ADORA2A (0.66) | ADORA2A | |
| SCHEMBL6871980 | 0.85 | ADORA2A (0.79) | ADORA2A | |
| SCHEMBL6869719 | 0.85 | ADORA2A (0.61) | ADORA2A | |
| SCHEMBL6872048 | 0.84 | ADORA2A (0.59) | ADORA2A | |
| SCHEMBL6863742 | 0.83 | ADORA2A (0.52) | ADORA2A | |
| SCHEMBL6871702 | 0.82 | ADORA2A (0.77) | ADORA2A | |
| SCHEMBL6869682 | 0.80 | ADORA2A (0.62) | ADORA2A | |
| SCHEMBL6863432 | 0.79 | ADORA2A (0.59) | ADORA2A | |
| SCHEMBL7144637 | 0.78 | ADORA2A (0.55) | ADORA2A | |
| SCHEMBL6863123 | 0.78 | ADORA2A (0.60) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347974-B1 | AMINOTRIAZOLOPYRIDIINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |