Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 19/20 | 0.68 |
| ▸ | OPRK1 | P41145 | 17/20 | 0.68 |
| ▸ | OPRD1 | P41143 | 12/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6863348 | 1.00 | OPRM1 (0.68) | OPRM1OPRK1OPRD1 | |
| SCHEMBL6863304 | 0.98 | OPRM1 (0.68) | OPRM1OPRK1OPRD1 | |
| SCHEMBL6863300 | 0.98 | OPRM1 (0.68) | OPRM1OPRK1OPRD1 | |
| SCHEMBL8506310 | 0.98 | OPRM1 (0.68) | OPRM1OPRK1OPRD1 | |
| SCHEMBL8200098 | 0.98 | OPRM1 (0.67) | OPRM1OPRK1OPRD1 | |
| SCHEMBL8207914 | 0.98 | OPRM1 (0.67) | OPRM1OPRK1OPRD1 | |
| SCHEMBL8207917 | 0.98 | OPRM1 (0.67) | OPRM1OPRK1OPRD1 | |
| SCHEMBL8200094 | 0.98 | OPRM1 (0.67) | OPRM1OPRK1OPRD1 | |
| SCHEMBL8210041 | 0.91 | OPRM1 (0.62) | OPRM1OPRK1OPRD1 | |
| SCHEMBL8210038 | 0.91 | OPRM1 (0.62) | OPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0960111-B1 | MORPHINE DERIVATIVES WITH ANALGESIC ACTIVITY | CENES LTD (GB) | 2004-11-24 | — | — | EP | disclosed |
| US-6150524-A | MORPHINAN DERIVATIVES | CENES LTD. (GB) | 2000-11-21 | — | — | US | disclosed |
| EP-0960111-A1 | MORPHINE DERIVATIVES WITH ANALGESIC ACTIVITY | NYCOMED IMAGING AS (NO) | 1999-12-01 | — | — | EP | disclosed |
| WO-1997022606-A1 | MORPHINE DERIVATIVES WITH ANALGESIC ACTIVITY | NYCOMED IMAGING AS (NO) | 1997-06-26 | — | — | WO | disclosed |