SCHEMBL6863352

SCHEMBL6863352

Cc1c(CO)oc2cccc(OCCCN(C)Cc3cccnc3)c12

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NMT2 O60551 13/20 0.54
NMT1 P30419 13/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6870316 0.84 NMT2 (0.48) NMT2NMT1
SCHEMBL6871534 0.83 NMT2 (0.49) NMT2NMT1
SCHEMBL3470308 0.83 NMT2 (0.72) NMT2NMT1
SCHEMBL6874148 0.83 NMT2 (0.52) NMT2NMT1
SCHEMBL3478342 0.82 NMT2 (0.51) NMT2NMT1
SCHEMBL6871652 0.81 NMT2 (0.79) NMT2NMT1
SCHEMBL3472926 0.80 NMT2 (0.46) NMT2NMT1
SCHEMBL7889754 0.78 NMT2 (0.52) NMT2NMT1
SCHEMBL3473586 0.78 NMT2 (0.51) NMT2NMT1
SCHEMBL3470583 0.77 NMT2 (0.41) NMT2NMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1149094-B1 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS BASILEA PHARMACEUTICA AG (CH) 2004-04-21 EP disclosed
US-6376491-B1 BENZOFURAN DERIVATIVES FOR TREATMENT OR PREVENTION OF MYCOSIS IN MAMMALS BASILEA PHARMACEUTICA AG (CH) 2002-04-23 US disclosed
EP-1149094-A2 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS Basilea Pharmaceutica AG (CH) 2001-10-31 EP disclosed
WO-2000037464-A2 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS BASILEA PHARMACEUTICA AG (CH) 2000-06-29 WO disclosed