SCHEMBL6863486

SCHEMBL6863486

Cc1c(CSc2ccccc2)oc2cccc(OCCCc3ncccc3CN)c12

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NMT2 O60551 13/20 0.59
NMT1 P30419 13/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6870863 0.93 NMT2 (0.51) NMT2NMT1
SCHEMBL6870473 0.92 NMT2 (0.51) NMT2NMT1
SCHEMBL6873892 0.87 NMT2 (0.50) NMT2NMT1
SCHEMBL6869762 0.86 NMT2 (0.61) NMT2NMT1
SCHEMBL6873295 0.82 NMT2 (0.46) NMT2NMT1
SCHEMBL6870822 0.82 NMT2 (0.44) NMT2NMT1
SCHEMBL6871587 0.81 NMT2 (0.59) NMT2NMT1
SCHEMBL6864282 0.80 NMT2 (0.48) NMT2NMT1
SCHEMBL6869720 0.80 NMT2 (0.59) NMT2NMT1
SCHEMBL6873441 0.80 NMT2 (0.51) NMT2NMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1149094-B1 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS BASILEA PHARMACEUTICA AG (CH) 2004-04-21 EP claimed