SCHEMBL6863529

SCHEMBL6863529

Cc1c(C[S+]([O-])CCc2ccccc2)oc2cccc(OCCCC(N)c3cccnc3)c12

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NMT2 O60551 14/20 0.52
NMT1 P30419 14/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3472632 0.88 NMT2 (0.66) NMT2NMT1
SCHEMBL3470224 0.84 NMT2 (0.54) NMT2NMT1
SCHEMBL3470844 0.82 NMT2 (0.78) NMT2NMT1
SCHEMBL3477446 0.82 NMT2 (0.47) NMT2NMT1
SCHEMBL7892884 0.81 NMT2 (0.55) NMT2NMT1
SCHEMBL3471290 0.80 NMT2 (0.65) NMT2NMT1
SCHEMBL3477172 0.79 NMT2 (0.57) NMT2NMT1
SCHEMBL6870672 0.79 NMT2 (0.49) NMT2NMT1
SCHEMBL3470765 0.78 NMT2 (0.65) NMT2NMT1
SCHEMBL6863521 0.78 NMT2 (0.49) NMT2NMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1149094-B1 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS BASILEA PHARMACEUTICA AG (CH) 2004-04-21 EP claimed
US-6376491-B1 BENZOFURAN DERIVATIVES FOR TREATMENT OR PREVENTION OF MYCOSIS IN MAMMALS BASILEA PHARMACEUTICA AG (CH) 2002-04-23 US claimed
EP-1149094-B1 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS BASILEA PHARMACEUTICA AG (CH) 2004-04-21 EP disclosed
US-6376491-B1 BENZOFURAN DERIVATIVES FOR TREATMENT OR PREVENTION OF MYCOSIS IN MAMMALS BASILEA PHARMACEUTICA AG (CH) 2002-04-23 US disclosed