Sugi Predict

Sugi Predict / Compounds / SCHEMBL6863567

SCHEMBL6863567

SCHEMBL6863567

CCCc1c(OCCCOc2cc(O)c(-c3cnc(S(=O)(=O)Cc4ccccc4)[nH]3)cc2CC)cccc1Oc1ccccc1C(=O)OC

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ LTB4R Q15722 20/20 0.55
▸ LTB4R2 Q9NPC1 19/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6808251 0.85 LTB4R (0.56) LTB4RLTB4R2
SCHEMBL6807216 0.81 LTB4R (0.60) LTB4RLTB4R2
SCHEMBL6892457 0.78 LTB4R (0.83) LTB4RLTB4R2
SCHEMBL6807256 0.78 LTB4R (0.64) LTB4RLTB4R2
SCHEMBL6812024 0.77 LTB4R (0.48) LTB4RLTB4R2
SCHEMBL6807250 0.76 LTB4R (0.51) LTB4RLTB4R2
SCHEMBL6808662 0.75 LTB4R (0.61) LTB4RLTB4R2
SCHEMBL6807968 0.75 LTB4R (0.61) LTB4RLTB4R2
SCHEMBL6806628 0.75 LTB4R (0.61) LTB4RLTB4R2
SCHEMBL6810836 0.75 LTB4R (0.61) LTB4RLTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6797723-B1 Heterocycle substituted diphenyl leukotriene antagonists ELI LILLY AND COMPANY 2004-09-28 — — US disclosed