Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 5/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6863316 | 0.86 | CXCR3 (0.46) | CXCR3KCNH2CACNA1IUSP30BRD4 | |
| SCHEMBL6863377 | 0.86 | CXCR3 (0.46) | CXCR3KCNH2CACNA1IUSP30BRD4 | |
| SCHEMBL12005297 | 0.80 | CXCR3 (0.46) | CXCR3KCNH2CACNA1IUSP30BRD4 | |
| SCHEMBL12005445 | 0.80 | CXCR3 (0.46) | CXCR3KCNH2CACNA1IUSP30BRD4 | |
| SCHEMBL12005295 | 0.80 | CXCR3 (0.46) | CXCR3KCNH2CACNA1IUSP30BRD4 | |
| SCHEMBL14433885 | 0.77 | MAPT (0.55) | CXCR3KCNH2CACNA1IUSP30MAPT | |
| SCHEMBL1443815 | 0.77 | KDM4E (0.54) | CXCR3KCNH2CACNA1IUSP30BRD4 | |
| SCHEMBL12015273 | 0.74 | CXCR3 (0.43) | CXCR3EPHX2GAA | |
| SCHEMBL6863997 | 0.73 | EPHX2 (0.47) | CXCR3KCNH2CACNA1IUSP30BRD4 | |
| SCHEMBL21859180 | 0.73 | MAPT (0.57) | CXCR3MAPTEPHX2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011032291-A1 | SELECTIVE CALCIUM CHANNEL MODULATORS | ZALICUS PHARMACEUTICALS LTD . (CA) | 2011-03-24 | — | — | WO | disclosed |