Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | XIAP | P98170 | 1/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16447715 | 0.81 | ALPI (0.53) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL27481507 | 0.79 | KDM4E (0.54) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL7038036 | 0.75 | KDM4E (0.58) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL1153493 | 0.74 | KDM4E (0.61) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL1153491 | 0.74 | KDM4E (0.61) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL8540631 | 0.74 | KDM4E (0.61) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL3843513 | 0.74 | SLC6A2 (0.58) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL14038762 | 0.74 | SLC6A2 (0.58) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL10253191 | 0.74 | SLC6A2 (0.58) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL4551685 | 0.74 | ALPI (0.53) | ALPIPKMPTGS1XIAPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040005274-A1 | Targeting multimeric imaging agents through multilocus binding | EPIX MEDICAL, INC., A DELAWARE CORPORATION | 2004-01-08 | — | — | US | disclosed |
| US-6652835-B1 | Improved relaxivity properties upon binding | EPIX MEDICAL, INC. | 2003-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040005274-A1 | Targeting multimeric imaging agents through multilocus binding | ILK, PBRM1, FABP1 | ALPI 4579/4885PKM 260/4885PTGS1 4495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.