Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CPA3 | P15088 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5864392 | 0.79 | CA2 (0.49) | CYP1A2TSHRHPGDMMP12MMP13 | |
| SCHEMBL4891863 | 0.79 | CA2 (0.49) | CYP1A2TSHRHPGDMMP12MMP13 | |
| SCHEMBL4891856 | 0.79 | CA2 (0.49) | CYP1A2TSHRHPGDMMP12MMP13 | |
| SCHEMBL5863374 | 0.76 | KMT2A (0.45) | CYP1A2TSHRHPGDMMP12MMP13 | |
| SCHEMBL3249841 | 0.71 | CA2 (0.48) | CYP1A2TSHR | |
| SCHEMBL265577 | 0.71 | CYP1A2 (0.61) | TBXAS1CYP1A2CPA3FOLH1TSHR | |
| SCHEMBL265135 | 0.71 | CYP1A2 (0.61) | TBXAS1CYP1A2CPA3FOLH1TSHR | |
| SCHEMBL65930 | 0.71 | CYP1A2 (0.61) | TBXAS1CYP1A2CPA3FOLH1TSHR | |
| SCHEMBL27514358 | 0.69 | CYP1A2 (0.59) | TBXAS1CYP1A2CPA3FOLH1TSHR | |
| Water SCHEMBL10936876 | 0.69 | CYP1A2 (0.59) | TBXAS1CYP1A2CPA3FOLH1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1052250-B1 | Sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors | SEARLE & CO (US) | 2004-07-14 | — | — | EP | disclosed |