Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.39 |
| ▸ | RHOC | P08134 | 1/20 | 0.37 |
| ▸ | RHOA | P61586 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ACP1 | P24666 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12004818 | 0.91 | NAMPT (0.44) | NAMPTRHOCRHOATACR1CACNA1G | |
| SCHEMBL6863401 | 0.91 | NAMPT (0.44) | NAMPTRHOCRHOATACR1CACNA1G | |
| SCHEMBL12004817 | 0.91 | NAMPT (0.44) | NAMPTRHOCRHOATACR1CACNA1G | |
| SCHEMBL6863467 | 0.84 | RHOC (0.43) | NAMPTRHOCRHOACACNA1GCACNA1H | |
| SCHEMBL6864138 | 0.84 | RHOC (0.43) | NAMPTRHOCRHOACACNA1GCACNA1H | |
| SCHEMBL6863915 | 0.84 | RHOC (0.43) | NAMPTRHOCRHOACACNA1GCACNA1H | |
| SCHEMBL12005749 | 0.84 | RHOC (0.43) | NAMPTRHOCRHOACACNA1GCACNA1H | |
| SCHEMBL12004714 | 0.82 | EPHX2 (0.46) | NAMPTRHOCRHOACACNA1GCACNA1H | |
| SCHEMBL6863390 | 0.82 | EPHX2 (0.46) | NAMPTRHOCRHOACACNA1GCACNA1H | |
| SCHEMBL6863159 | 0.82 | EPHX2 (0.46) | NAMPTRHOCRHOACACNA1GCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011032291-A1 | SELECTIVE CALCIUM CHANNEL MODULATORS | ZALICUS PHARMACEUTICALS LTD . (CA) | 2011-03-24 | — | — | WO | disclosed |