SCHEMBL6864171

SCHEMBL6864171

Cc1c(OC(=O)NNc2ccc(F)cc2)oc2cccc(OCCCNCc3cccnc3)c12

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NMT2 O60551 17/20 0.64
NMT1 P30419 17/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3476012 0.87 NMT2 (0.74) NMT2NMT1
SCHEMBL6869373 0.86 NMT2 (0.57) NMT2NMT1
SCHEMBL6863882 0.85 NMT2 (0.76) NMT2NMT1
SCHEMBL6868241 0.85 NMT2 (0.66) NMT2NMT1
SCHEMBL6871538 0.85 NMT2 (0.67) NMT2NMT1
SCHEMBL6871625 0.84 NMT2 (0.64) NMT2NMT1
SCHEMBL6871935 0.84 NMT2 (0.62) NMT2NMT1
SCHEMBL6868367 0.83 NMT2 (0.65) NMT2NMT1
SCHEMBL6869342 0.83 NMT2 (0.63) NMT2NMT1
SCHEMBL6874419 0.83 NMT2 (0.75) NMT2NMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1149094-B1 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS BASILEA PHARMACEUTICA AG (CH) 2004-04-21 EP claimed