Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 17/20 | 0.66 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6865325 | 0.89 | GPR52 (0.55) | GPR52 | |
| SCHEMBL13506797 | 0.89 | GPR52 (0.66) | GPR52GRIA2GRIN1GRIN2A | |
| SCHEMBL13505894 | 0.86 | GPR52 (0.55) | GPR52GRIA2GRIN1GRIN2A | |
| SCHEMBL6865069 | 0.86 | GPR52 (0.65) | GPR52 | |
| SCHEMBL13506211 | 0.83 | GPR52 (0.53) | GPR52 | |
| SCHEMBL6864185 | 0.83 | GPR52 (0.69) | GPR52 | |
| SCHEMBL6864852 | 0.83 | GPR52 (0.58) | GPR52GRIA2GRIN1GRIN2A | |
| SCHEMBL3221644 | 0.82 | GPR52 (0.71) | GPR52 | |
| SCHEMBL13506233 | 0.82 | GPR52 (0.81) | GPR52GRIA2GRIN1GRIN2A | |
| SCHEMBL6864122 | 0.82 | GPR52 (0.66) | GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2518054-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011078360-A1 | AMIDE COMPOUND | 武田薬品工業株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |