Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 15/20 | 0.67 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6864201 | 0.91 | GPR52 (0.68) | GPR52 | |
| SCHEMBL6864277 | 0.90 | GPR52 (0.53) | GPR52CHRM4SCDPPARA | |
| SCHEMBL13506153 | 0.88 | SMN1; SMN2 (0.54) | GPR52SCDPPARA | |
| SCHEMBL6864575 | 0.87 | GPR52 (0.52) | GPR52 | |
| SCHEMBL13505649 | 0.85 | GPR52 (0.50) | GPR52 | |
| SCHEMBL3196264 | 0.83 | GPR52 (0.73) | GPR52 | |
| SCHEMBL3207056 | 0.80 | GPR52 (1.00) | GPR52 | |
| SCHEMBL13505964 | 0.80 | GPR52 (0.53) | GPR52 | |
| SCHEMBL7961131 | 0.80 | GPR52 (0.80) | GPR52 | |
| SCHEMBL6863606 | 0.80 | GPR52 (0.67) | GPR52CHRM4PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2518054-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011078360-A1 | AMIDE COMPOUND | 武田薬品工業株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |