Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 16/20 | 0.64 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13505541 | 0.91 | GPR52 (0.59) | GPR52SCD | |
| SCHEMBL6864488 | 0.91 | GPR52 (0.79) | GPR52 | |
| SCHEMBL6864650 | 0.91 | GPR52 (0.59) | GPR52 | |
| SCHEMBL6864362 | 0.90 | GPR52 (0.61) | GPR52SCD | |
| SCHEMBL6866231 | 0.90 | GPR52 (0.64) | GPR52SCDGRIA2GRIN1GRIN2A | |
| SCHEMBL13506758 | 0.88 | GPR52 (0.57) | GPR52SCD | |
| SCHEMBL6864345 | 0.86 | GPR52 (0.54) | GPR52SCDGRIA2GRIN1GRIN2A | |
| SCHEMBL13505719 | 0.84 | GPR52 (0.62) | GPR52SCD | |
| SCHEMBL6865522 | 0.83 | GPR52 (0.61) | GPR52 | |
| SCHEMBL6864245 | 0.83 | GPR52 (0.79) | GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2518054-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011078360-A1 | AMIDE COMPOUND | 武田薬品工業株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |