Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 16/20 | 0.60 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6864979 | 0.90 | GPR52 (0.69) | GPR52 | |
| SCHEMBL6864254 | 0.86 | GPR52 (0.55) | GPR52MTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL13505872 | 0.84 | GPR52 (0.51) | GPR52MTNR1AMTNR1B | |
| SCHEMBL6864272 | 0.83 | GPR52 (0.50) | GPR52 | |
| SCHEMBL13505650 | 0.83 | GPR52 (0.49) | GPR52 | |
| SCHEMBL13505642 | 0.75 | GPR52 (1.00) | GPR52 | |
| SCHEMBL6864796 | 0.75 | GPR52 (0.77) | GPR52 | |
| SCHEMBL6864495 | 0.72 | GPR52 (1.00) | GPR52 | |
| SCHEMBL6864488 | 0.72 | GPR52 (0.79) | GPR52 | |
| SCHEMBL6864628 | 0.71 | GPR52 (0.62) | GPR52NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2518054-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011078360-A1 | AMIDE COMPOUND | 武田薬品工業株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |