SCHEMBL6864591

SCHEMBL6864591

O=C(O)c1ccc2cc3cc(C(=O)O)c(C(=O)O)cc3cc2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.55
PTPN1 P18031 2/20 0.53
PTPN11 Q06124 1/20 0.49
TP53 P04637 1/20 0.46
TSHR P16473 1/20 0.46
ALDH1A1 P00352 1/20 0.46
HPGD P15428 1/20 0.46
ENPP2 Q13822 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
SRPK1 Q96SB4 1/20 0.45
RPS6KB2 Q9UBS0 1/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
POLB P06746 1/20 0.45
GAA P10253 1/20 0.45
MAPT P10636 1/20 0.45
CA4 P22748 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31444254 1.00 KDM4E (0.55) KDM4EPTPN1PTPN11TP53TSHR
SCHEMBL29729046 0.98 KDM4E (0.57) KDM4EPTPN1PTPN11TP53TSHR
SCHEMBL464946 0.98 KDM4E (0.57) KDM4EPTPN1PTPN11TP53TSHR
SCHEMBL30151493 0.98 KDM4E (0.57) KDM4EPTPN1PTPN11TP53TSHR
SCHEMBL1951984 0.91 KDM4E (0.63) KDM4EPTPN1TP53TSHRALDH1A1
SCHEMBL1551731 0.91 KDM4E (0.63) KDM4EPTPN1TP53TSHRALDH1A1
SCHEMBL258253 0.91 KDM4E (0.63) KDM4EPTPN1TP53TSHRALDH1A1
SCHEMBL1552467 0.91 KDM4E (0.63) KDM4EPTPN1TP53TSHRALDH1A1
SCHEMBL29451113 0.91 KDM4E (0.63) KDM4EPTPN1TP53TSHRALDH1A1
SCHEMBL20489383 0.89 PTPN1 (0.61) KDM4EPTPN1PTPN11TP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6291707-B1 DISSOLVING ORGANIC ACID, OR ITS DERIVATIVE IN A BASE COMPOUND SELECTED FROM OF AMINES AND MORPHOLINES; REMOVING IMPURITIES; RECOVERING ACID OR ITS DERIVATIVE; REMOVING ADSORBED BASE COMPOUND TO OBTAIN PURIFIED ACID OR ITS DERIVATIVE LIN TSONG-DAR VINCENT (US) 2001-09-18 US claimed
US-6392091-B1 None US disclosed
US-20220185939-A1 POLYOL COMPOSITION FOR PRODUCING FLEXIBLE POLYURETHANE FOAM, AND FLEXIBLE POLYURETHANE FOAM SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2022-06-16 US disclosed
EP-2639250-B1 URETHANE RESIN PARTICLES SANYO CHEMICAL IND LTD (JP) 2021-01-06 EP disclosed
EP-2832754-B1 VINYL RESIN AND RESIN COMPOSITION SANYO CHEMICAL IND LTD (JP) 2020-10-28 EP disclosed
EP-2781529-B1 Strength-improving agent for production of polyurethane foam SANYO CHEMICAL IND LTD (JP) 2020-07-08 EP disclosed
EP-2562193-B1 POLYOL FOR POLYURETHANE PREPARATION AND POLYURETHANE PREPARATION METHOD USING SAME SANYO CHEMICAL IND LTD (JP) 2018-10-17 EP disclosed
EP-2730597-B1 POLYURETHANE RESIN FOR MOISTURE-PERMEABLE WATER-PROOF MATERIALS, AND POLYURETHANE RESIN COMPOSITION SANYO CHEMICAL IND LTD (JP) 2018-06-13 EP disclosed
US-9550874-B2 Powdered polyurethane urea resin composition for slush molding and manufacturing process therefor SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2017-01-24 US disclosed
US-9499655-B2 Polyurethane resin for moisture-permeable water-proof materials, and polyurethane resin composition SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2016-11-22 US disclosed
EP-1131276-A4 PROCESS OF PURIFYING AND PRODUCING HIGH PURITY AROMATIC POLYCARBOXYLIC ACIDS AND DERIVATIVES THEREOF LIN TSONG-DAR VINCENT (US) 2002-09-18 EP disclosed
US-6392091-B2 SOLVENT EXTRACTION LIN TSONG-DAR VINCENT (US) 2002-05-21 US disclosed
CN-1332714-A Method for purifying and producing high-purity aromatic polycarboxylic acid and derivatives thereof VINCENT T D LIN (US) 2002-01-23 CN disclosed
US-20020002304-A1 PROCESS OF PURIFYING AND PRODUCING HIGH PURITY AROMATIC POLYCARBOXYLIC ACIDS LIN TSONG-DAR VINCENT (US) 2002-01-03 US disclosed
US-6291707-B1 DISSOLVING ORGANIC ACID, OR ITS DERIVATIVE IN A BASE COMPOUND SELECTED FROM OF AMINES AND MORPHOLINES; REMOVING IMPURITIES; RECOVERING ACID OR ITS DERIVATIVE; REMOVING ADSORBED BASE COMPOUND TO OBTAIN PURIFIED ACID OR ITS DERIVATIVE LIN TSONG-DAR VINCENT (US) 2001-09-18 US disclosed
EP-1131276-A1 PROCESS OF PURIFYING AND PRODUCING HIGH PURITY AROMATIC POLYCARBOXYLIC ACIDS AND DERIVATIVES THEREOF Lin, Tsong-Dar Vincent (US) 2001-09-12 EP disclosed
EP-1111442-A1 TREATING AGENT FOR LIQUID CRYSTAL ALIGNMENT LAYER AND LIQUID CRYSTAL DEVICE USING THE SAME, AND METHOD FOR ALIGNMENT OF LIQUID CRYSTAL Nissan Chemical Industries, Ltd. (JP) 2001-06-27 EP disclosed
US-6133476-A DISSOLVING A SALT FORMED BY CRUDE AROMATIC POLYCARBOXYLIC ACID AND A MORPHOLINE COMPOUND IN A CO-SOLVENT; REMOVING IMPURITIES; ADDING AN ACID SOLVENT TO THE SALT OR THERMALLY DECOMPOSING THE SALT. LIN TSONG-DAR VINCENT (US) 2000-10-17 US disclosed
WO-2000031014-A1 PROCESS OF PURIFYING AND PRODUCING HIGH PURITY AROMATIC POLYCARBOXYLIC ACIDS AND DERIVATIVES THEREOF LIN T D VINCENT (US) 2000-06-02 WO disclosed
WO-1998012157-A2 PROCESS FOR PURIFICATION OF AROMATIC POLYCARBOXYLIC ACIDS LIN, TSONG-DAR, VINCENT 1998-03-26 WO disclosed