SCHEMBL6864609

SCHEMBL6864609

C=CCOC(=O)OCCn1c(=O)n(CCOC(=O)OCC=C)c(=O)n(CCOC(=O)OCC=C)c1=O

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.38
NPSR1 Q6W5P4 3/20 0.36
ALDH1A1 P00352 2/20 0.34
PLA2G4A P47712 1/20 0.33
GAA P10253 2/20 0.33
TSHR P16473 2/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
CACNA1B Q00975 1/20 0.32
APBA1 Q02410 1/20 0.32
KDM4E B2RXH2 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22899021 0.80 ALDH1A1 (0.35) CYP3A4NPSR1ALDH1A1PLA2G4AGAA
SCHEMBL4193243 0.78 CYP3A4 (0.34) CYP3A4NPSR1ALDH1A1TSHRHSD17B10
SCHEMBL176184 0.78 CYP3A4 (0.43) CYP3A4NPSR1ALDH1A1GAATSHR
SCHEMBL21931989 0.77 TSHR (0.46) CYP3A4NPSR1ALDH1A1PLA2G4ATSHR
SCHEMBL2367695 0.76 HTT (0.42) CYP3A4NPSR1ALDH1A1PLA2G4AGAA
SCHEMBL11763831 0.76 TSHR (0.47) CYP3A4NPSR1ALDH1A1GAATSHR
Ethylene SCHEMBL167446 0.76 CYP3A4 (0.42) CYP3A4NPSR1ALDH1A1GAATSHR
SCHEMBL9928 0.76 CYP3A4 (0.48) CYP3A4NPSR1ALDH1A1GAATSHR
SCHEMBL42549 0.76 TSHR (0.52) CYP3A4NPSR1ALDH1A1PLA2G4AGAA
SCHEMBL10382272 0.75 ALDH1A1 (0.46) CYP3A4NPSR1ALDH1A1PLA2G4AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10822455-B2 Composition for optical articles and optical articles made therewith PPG INDUSTRIES OHIO, INC. (US) 2020-11-03 US claimed
EP-3500605-B1 POLYMERIZABLE COMPOSITION FOR OPTICAL ARTICLES PPG IND OHIO INC (US) 2020-05-20 EP claimed
US-20190352458-A1 Composition for Optical Articles and Optical Articles Made Therewith PPG INDUSTRIES OHIO, INC. 2019-11-21 US claimed
US-10407540-B2 Composition for optical articles and optical articles made therewith PPG INDUSTRIES OHIO, INC. (US) 2019-09-10 US claimed
EP-3347383-B1 COMPOSITION FOR OPTICAL ARTICLES AND OPTICAL ARTICLES MADE THEREWITH PPG IND OHIO INC (US) 2019-08-21 EP claimed
US-10294318-B2 Polymerizable composition for optical articles PPG INDUSTRIES OHIO, INC. (US) 2019-05-21 US claimed
US-20180051115-A1 Polymerizable Composition for Optical Articles PPG INDUSTRIES OHIO, INC. 2018-02-22 US claimed
EP-0201978-B1 PROCESS FOR THE PREPARATION OF SUBSTITUTES FOR OPTICAL GLASSES AND POLYMERIZABLE LIQUID COMPOSITION SUITABLE TO THAT PURPOSE ENICHEM SYNTHESIS S.p.A. (IT) 1992-12-02 EP claimed
US-4835233-A Liquid polymerizable compositions for the production of substitutes for optical glasses ENICHEM SINTESI S.P.A. (IT) 1989-05-30 US claimed
US-4812545-A BASED ON ALLYLCARBONATES ENICHEM SINTESI S.P.A. (IT) 1989-03-14 US claimed
EP-0227178-A2 Liquid, polymerizable composition for the production of substitutes for optical glasses ENICHEM SYNTHESIS S.p.A. (IT) 1987-07-01 EP claimed
EP-0201978-A2 Process for the preparation of substitutes for optical glasses and polymerizable liquid composition suitable to that purpose ENICHEM SYNTHESIS S.p.A. (IT) 1986-11-20 EP claimed
EP-3840925-B1 METHOD FOR PREPARING A MOLDED POLYMERIC ARTICLE PPG IND OHIO INC (US) 2022-11-23 EP disclosed
EP-3780226-B1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY MITSUBISHI CHEM CORP (JP) 2022-05-11 EP disclosed
US-20210331354-A1 Method for Preparing a Molded Polymeric Article PPG INDUSTRIES OHIO, INC. 2021-10-28 US disclosed
US-11028206-B2 Polymerizable composition for optical articles PPG INDUSTRIES OHIO, INC. (US) 2021-06-08 US disclosed
US-4812545-A BASED ON ALLYLCARBONATES ENICHEM SINTESI S.P.A. (IT) 1989-03-14 US disclosed
EP-0302537-A1 Liquid composition polymerizable to yield organic glasses endowed with high thermal stability ENICHEM SYNTHESIS S.p.A. (IT) 1989-02-08 EP disclosed
EP-0201978-A2 Process for the preparation of substitutes for optical glasses and polymerizable liquid composition suitable to that purpose ENICHEM SYNTHESIS S.p.A. (IT) 1986-11-20 EP disclosed
EP-0201978-A2 Process for the preparation of substitutes for optical glasses and polymerizable liquid composition suitable to that purpose ENICHEM SYNTHESIS S.p.A. (IT) 1986-11-20 EP disclosed