Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRNG | P07510 | 1/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2967632 | 0.84 | GABRA1 (0.43) | HIF1AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL1887520 | 0.79 | HSP90AA1 (0.38) | MAPTNPSR1MAOBCHRNB2SLC6A2 | |
| SCHEMBL29416859 | 0.79 | HSP90AA1 (0.38) | MAPTNPSR1MAOBCHRNB2SLC6A2 | |
| SCHEMBL6875188 | 0.75 | MEN1 (0.56) | MEN1KMT2AMAPTKDM4ENPSR1 | |
| SCHEMBL7755343 | 0.73 | TP53 (0.52) | HIF1AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL7521156 | 0.72 | CYP19A1 (0.50) | MEN1KMT2AMAPTKDM4ENPSR1 | |
| SCHEMBL17509392 | 0.70 | SLC6A2 (0.46) | MEN1KMT2AMAPTKDM4ENPSR1 | |
| SCHEMBL6565634 | 0.70 | KMT2A (0.43) | MEN1KMT2AMAPTKDM4ENPSR1 | |
| SCHEMBL25194801 | 0.69 | CYP3A4 (0.57) | HIF1AMEN1KMT2AMAPTKDM4E | |
| SCHEMBL30991587 | 0.69 | CYP3A4 (0.57) | HIF1AMEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414476-A1 | BAUHINIA EXTRACTS | MERCK PATENT GmbH (DE) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003011311-A1 | BAUHINIA EXTRACTS | MERCK PATENT GMBH (DE) | 2003-02-13 | — | — | WO | disclosed |