SCHEMBL6865288

SCHEMBL6865288

O=S(=O)(O)c1cccc(Nc2ccccc2)c1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 2/20 0.72
NSD2 O96028 2/20 0.60
CASP6 P55212 2/20 0.60
DUSP3 P51452 1/20 0.60
PTPN5 P54829 1/20 0.60
CASP7 P55210 1/20 0.60
PTPN11 Q06124 1/20 0.60
MAPT P10636 4/20 0.56
TSHR P16473 3/20 0.56
ALDH1A1 P00352 3/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
AR P10275 1/20 0.56
CYP3A4 P08684 1/20 0.52
CASR P41180 3/20 0.51
TDP1 Q9NUW8 3/20 0.50
HSD17B10 Q99714 2/20 0.50
TNNI3 P19429 1/20 0.50
TNNT2 P45379 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9717494 0.95 SNCA (0.76) SNCANSD2CASP6DUSP3PTPN5
SCHEMBL18421634 0.88 SNCA (0.62) SNCANSD2CASP6DUSP3PTPN5
Diphenylamine SCHEMBL28417536 0.88 TSHR (0.73) SNCANSD2CASP6DUSP3PTPN5
SCHEMBL10490044 0.86 SNCA (0.59) SNCANSD2CASP6DUSP3PTPN5
SCHEMBL10346491 0.86 SNCA (0.59) SNCANSD2CASP6DUSP3PTPN5
SCHEMBL10570982 0.86 SNCA (0.55) SNCANSD2CASP6DUSP3PTPN5
SCHEMBL11742527 0.84 SNCA (0.77) SNCANSD2CASP6DUSP3PTPN5
SCHEMBL19747087 0.84 MAPT (0.60) SNCAMAPTTSHRALDH1A1MEN1
SCHEMBL29843770 0.84 SNCA (1.00) SNCANSD2CASP6DUSP3PTPN5
SCHEMBL278412 0.84 SNCA (1.00) SNCANSD2CASP6DUSP3PTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1177967-C Enzymatic method for textile dyeing ŵ����÷�����޹�˾ 2004-12-01 CN claimed
US-6805718-B2 USING AROMATIC AMINE, NAPHTHOL OR AMINONAPHTHALENE AND ENZYME NOVOZYMES A/S (DK) 2004-10-19 US claimed
US-20030226215-A1 Enzymatic method for textile dying NOVOZYMES NORTH AMERICA, INC. (US) 2003-12-11 US claimed
EP-1266068-A1 ENZYMATIC METHOD FOR TEXTILE DYEING Novozymes North America, Inc. (US) 2002-12-18 EP claimed
US-20010037532-A1 Enzymatic method for textile dyeing NOVOZYMES A/S (DK) 2001-11-08 US claimed
US-6296672-B1 PEROXIDASE, OXIDOREDUCTASE, LACCASE NOVOZYMES A/S PATENTS (DK) 2001-10-02 US claimed
WO-2001044563-A1 ENZYMATIC METHOD FOR TEXTILE DYEING NOVOZYMES NORTH AMERICA, INC. (US) 2001-06-21 WO claimed
CN-1229099-C Use of reactive dyes for dyeing hair BASF AG (DE) 2005-11-30 CN disclosed
CN-1177967-C Enzymatic method for textile dyeing ŵ����÷�����޹�˾ 2004-12-01 CN disclosed
US-6805718-B2 USING AROMATIC AMINE, NAPHTHOL OR AMINONAPHTHALENE AND ENZYME NOVOZYMES A/S (DK) 2004-10-19 US disclosed
US-20030226215-A1 Enzymatic method for textile dying NOVOZYMES NORTH AMERICA, INC. (US) 2003-12-11 US disclosed
CN-1104472-C Reactive dyes with heterocyclic anchor BASF AG (DE) 2003-04-02 CN disclosed
CN-1104471-C Double reactive dyes BASF AG (DE) 2003-04-02 CN disclosed
US-20010037532-A1 Enzymatic method for textile dyeing NOVOZYMES A/S (DK) 2001-11-08 US disclosed
US-6296672-B1 PEROXIDASE, OXIDOREDUCTASE, LACCASE NOVOZYMES A/S PATENTS (DK) 2001-10-02 US disclosed
CN-1268156-A Double reactive dyes BASF AG (DE) 2000-09-27 CN disclosed
CN-1264284-A Application of reactive dye in hair dyeing BASF AG (DE) 2000-08-23 CN disclosed
CN-1239493-A Reactive dyes with heterocyclic anchor points BASF AG (DE) 1999-12-22 CN disclosed
CN-1145935-A Reactive dyes with benzo-fused heterocycle as anchor BASF AG (DE) 1997-03-26 CN disclosed
US-5380456-A Aromatic aminosulfonic acid, liquid bleach UNITED STATES BORAX & CHEMICAL CORPORATION (US) 1995-01-10 US disclosed