Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 5/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | PCNA | P12004 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14387746 | 0.90 | HDAC1 (0.53) | FFAR1HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL28001015 | 0.89 | TPSAB1 (0.54) | TPSAB1LOXL2HDAC1HDAC6HDAC2 | |
| SCHEMBL22526771 | 0.87 | TPSAB1 (0.53) | TPSAB1LOXL2HDAC1HDAC6HDAC2 | |
| SCHEMBL6821715 | 0.85 | GFER (0.48) | FFAR1HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL12507197 | 0.82 | POLB (0.59) | FFAR1HDAC1ALDH1A1POLBGAA | |
| SCHEMBL13609517 | 0.82 | HDAC2 (0.62) | HDAC1HDAC2HDAC8ALDH1A1POLB | |
| SCHEMBL31581014 | 0.81 | PLA2G10 (0.50) | FFAR1HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL1128782 | 0.81 | TAAR1 (0.52) | FFAR1HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL10094799 | 0.81 | HDAC1 (0.70) | FFAR1HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL6241724 | 0.81 | CYP1A2 (0.57) | FFAR1HDAC1HDAC6HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110053925-A1 | Hydroxamate-Based Inhibitors of Deacetylases | NOVARTIS AG | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053925-A1 | Hydroxamate-Based Inhibitors of Deacetylases | HDAC1, HDAC11, HDAC3 | TPSAB1 1080/4885LOXL2 3243/4885FFAR1 874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.