Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 12/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6864973 | 0.89 | GPR52 (0.81) | GPR52 | |
| SCHEMBL6864696 | 0.89 | GPR52 (0.61) | GPR52NPC1RAB9AHPGDWNT3A | |
| SCHEMBL6863895 | 0.89 | GPR52 (0.80) | GPR52NPC1RAB9AHPGDWNT3A | |
| SCHEMBL6863958 | 0.88 | GPR52 (0.59) | GPR52NPC1RAB9AHPGDWNT3A | |
| SCHEMBL6864527 | 0.85 | GPR52 (0.60) | GPR52NPC1RAB9AHPGDWNT3A | |
| SCHEMBL13506727 | 0.85 | GPR52 (0.59) | GPR52NPC1RAB9AHPGDWNT3A | |
| SCHEMBL13506218 | 0.85 | GPR52 (0.57) | GPR52NPC1RAB9AHPGDWNT3A | |
| SCHEMBL13506490 | 0.83 | GPR52 (0.83) | GPR52 | |
| SCHEMBL13505504 | 0.82 | GPR52 (0.57) | GPR52HPGD | |
| SCHEMBL6863851 | 0.81 | GPR52 (0.83) | GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2518054-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011078360-A1 | AMIDE COMPOUND | 武田薬品工業株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |