Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 5/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30766038 | 0.79 | KMT2A (0.50) | MEN1KMT2AL3MBTL1GAATSHR | |
| SCHEMBL4456432 | 0.75 | APEX1 (0.42) | MEN1KMT2AL3MBTL1GAAALDH1A1 | |
| SCHEMBL1988320 | 0.70 | ALDH1A1 (0.66) | MEN1KMT2AL3MBTL1GAATSHR | |
| SCHEMBL8642946 | 0.70 | KDM4E (0.46) | MEN1KMT2AGAATSHRALDH1A1 | |
| SCHEMBL30069317 | 0.69 | MEN1 (0.66) | MEN1KMT2AL3MBTL1GAATSHR | |
| SCHEMBL4399107 | 0.67 | GSK3A (0.69) | MEN1KMT2AL3MBTL1GAATSHR | |
| SCHEMBL30765923 | 0.67 | MEN1 (0.54) | MEN1KMT2AL3MBTL1GAATSHR | |
| SCHEMBL521967 | 0.66 | ALDH1A1 (0.83) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL15023923 | 0.65 | GSK3A (0.65) | MEN1KMT2AL3MBTL1TSHRALDH1A1 | |
| SCHEMBL14926801 | 0.65 | GSK3A (0.65) | MEN1KMT2AL3MBTL1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451175-A1 | THROMBIN INHIBITORS | University of Ljubljana (SI) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003048155-A1 | THROMBIN INHIBITORS | UNIVERSITY OF LJUBLJANA (SI) | 2003-06-12 | — | — | WO | disclosed |