SCHEMBL6865940

SCHEMBL6865940

O=C1NC(=O)/C(=C/c2ccc(OCC3CCCCC3)c(Cl)c2)S1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HPGD P15428 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL935673 1.00 HPGD (1.00) HPGD
SCHEMBL935672 1.00 HPGD (1.00) HPGD
SCHEMBL935699 0.89 HPGD (1.00) HPGD
SCHEMBL935697 0.89 HPGD (1.00) HPGD
SCHEMBL1299408 0.88 HPGD (1.00) HPGD
SCHEMBL1299406 0.88 HPGD (1.00) HPGD
SCHEMBL1299782 0.88 HPGD (1.00) HPGD
SCHEMBL6866689 0.88 HPGD (1.00) HPGD
SCHEMBL1299781 0.88 HPGD (1.00) HPGD
SCHEMBL1299814 0.87 HPGD (1.00) HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2383263-B1 NOVEL THIAZOLIDINEDIONE DERIVATIVE AND USE THEREOF UNIV CHOSUN IACF (KR) 2014-04-16 EP disclosed
US-8637558-B2 Thiazolidinedione derivative and use thereof INDUSTRY-ACADEMIC COOPERATION FOUNDATION, CHOSUN UNIVERSITY (KR) 2014-01-28 US disclosed
US-8637558-B2 Thiazolidinedione derivative and use thereof INDUSTRY-ACADEMIC COOPERATION FOUNDATION, CHOSUN UNIVERSITY (KR) 2014-01-28 US disclosed
US-20110269954-A1 NOVEL THIAZOLIDINEDIONE DERIVATIVE AND USE THEREOF INDUSTRY-ACADEMIC COOPERATION FOUNDATION, CHOSUN UNIVERSITY (KR) 2011-11-03 US disclosed
US-20110269954-A1 NOVEL THIAZOLIDINEDIONE DERIVATIVE AND USE THEREOF INDUSTRY-ACADEMIC COOPERATION FOUNDATION, CHOSUN UNIVERSITY (KR) 2011-11-03 US disclosed
WO-2010077101-A4 NOVEL THIAZOLIDINEDIONE DERIVATIVE AND USE THEREOF 조선대학교산학협력단 (KR) 2011-01-13 WO disclosed
WO-2010090458-A2 COMPOSITION FOR CONTROLLING HARMFUL ALGAE 조선대학교산학협력단 (KR) 2010-08-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110269954-A1 NOVEL THIAZOLIDINEDIONE DERIVATIVE AND USE THEREOF HPGD, CYP27B1, GCDH HPGD 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.