Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6865467 | 0.87 | SMN1; SMN2 (0.55) | SMN1; SMN2USP2NPC1RAB9AKDM4E | |
| SCHEMBL6868613 | 0.86 | SMN1; SMN2 (0.57) | SMN1; SMN2USP2NPC1RAB9AKDM4E | |
| SCHEMBL6859213 | 0.83 | SMN1; SMN2 (0.51) | SMN1; SMN2USP2NPC1RAB9AKDM4E | |
| SCHEMBL6866321 | 0.81 | SMN1; SMN2 (0.49) | SMN1; SMN2USP2NPC1RAB9AKDM4E | |
| SCHEMBL6866044 | 0.81 | SMN1; SMN2 (0.55) | SMN1; SMN2USP2NPC1RAB9AKDM4E | |
| SCHEMBL31248989 | 0.78 | SMN1; SMN2 (0.65) | SMN1; SMN2USP2NPC1RAB9AKDM4E | |
| SCHEMBL3746825 | 0.78 | SMN1; SMN2 (0.65) | SMN1; SMN2USP2NPC1RAB9AKDM4E | |
| SCHEMBL5610013 | 0.77 | SMN1; SMN2 (0.68) | SMN1; SMN2USP2NPC1RAB9AKDM4E | |
| SCHEMBL14685205 | 0.77 | SMN1; SMN2 (0.68) | SMN1; SMN2USP2NPC1RAB9AKDM4E | |
| SCHEMBL2518498 | 0.77 | LMNA (0.63) | SMN1; SMN2NPC1RAB9AKDM4EHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1008645-B1 | Detergent bleaching compositions | UNILEVER PLC (GB) | 2004-07-21 | — | — | EP | disclosed |
| US-6165963-A | Detergent bleaching composition comprising pentadentate ligand derivatives | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (US) | 2000-12-26 | — | — | US | disclosed |
| EP-1008645-A1 | Detergent bleaching compositions | UNILEVER PLC (GB) | 2000-06-14 | — | — | EP | disclosed |
| WO-2000027975-A1 | DETERGENT BLEACHING COMPOSITION | UNILEVER PLC (GB) | 2000-05-18 | — | — | WO | disclosed |