Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ILK | Q13418 | 19/20 | 0.67 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL686851 | 0.80 | ILK (1.00) | ILK | |
| SCHEMBL686780 | 0.77 | ILK (1.00) | ILK | |
| SCHEMBL686603 | 0.77 | ILK (0.70) | ILK | |
| SCHEMBL687641 | 0.64 | ILK (1.00) | ILK | |
| SCHEMBL687009 | 0.64 | ILK (1.00) | ILK | |
| SCHEMBL28902793 | 0.63 | SMN1; SMN2 (0.53) | — | |
| SCHEMBL3761940 | 0.63 | ILK (0.55) | ILK | |
| SCHEMBL686438 | 0.63 | ILK (1.00) | ILK | |
| SCHEMBL6279065 | 0.62 | ILK (0.86) | ILK | |
| SCHEMBL687535 | 0.62 | ILK (1.00) | ILK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1542997-B1 | PYRAZOLYLBENZOTHIAZOLE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | DERMIRA CANADA INC (CA) | 2012-02-29 | — | — | EP | claimed |