SCHEMBL68663

SCHEMBL68663

CCCC(c1ccc(O)c(C)c1)c1ccc(O)c(C)c1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 14/20 0.47
ESR2 Q92731 8/20 0.47
AR P10275 5/20 0.47
TP53 P04637 2/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
ALOX15 P16050 1/20 0.44
CYP2C19 P33261 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
PDE10A Q9Y233 1/20 0.41
TRPA1 O75762 1/20 0.38
PTGS1 P23219 1/20 0.38
CACNA1C Q13936 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9573429 0.93 ESR1 (0.43) ESR1ESR2ARTP53CYP2D6
SCHEMBL156611 0.93 ESR1 (0.47) ESR1ESR2ARTP53CYP2D6
SCHEMBL1594960 0.90 ESR1 (0.48) ESR1ESR2ARTP53CYP2D6
SCHEMBL31222316 0.90 ESR1 (0.48) ESR1ESR2ARTP53CYP2D6
SCHEMBL5301206 0.89 ESR1 (0.50) ESR1ESR2ARTP53TDP1
SCHEMBL31620718 0.87 ESR1 (0.49) ESR1ESR2ARTP53TDP1
SCHEMBL5710070 0.87 ESR1 (0.49) ESR1ESR2ARTP53TDP1
SCHEMBL1595673 0.86 ESR1 (0.45) ESR1ESR2ARTP53CYP2D6
SCHEMBL20520233 0.86 ESR1 (0.47) ESR1ESR2AR
SCHEMBL20520203 0.86 ESR1 (0.47) ESR1ESR2AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4609928-A LEUCO DYES, COLOR DEVELOPERS, BISHENOL, P-HYDROXYBENZOIC ACID ESTER, POROSITY, FILLERS RICOH COMPANY, LTD. (JP) 1986-09-02 US claimed
CN-110446770-A Reversible thermal discoloration composition and reversible thermal discoloration microcapsule pigment containing the same PILOT INK CO LTD 2019-11-12 CN disclosed
CN-108779238-A Polycarbonate resin, method for producing polycarbonate resin, coating liquid, electrophotographic photoreceptor, and electrophotographic apparatus 出光兴产株式会社 2018-11-09 CN disclosed
CN-108368027-A Bischloroformate composition, process for producing bischloroformate composition, solution containing bischloroformate composition, polycarbonate resin, process for producing polycarbonate resin, coating liquid, electrophotographic photoreceptor, and electrophotographic apparatus 出光兴产株式会社 2018-08-03 CN disclosed
CN-108137912-A Poly carbonate resin composition and the mechanograph by its production 乐天尖端材料株式会社 2018-06-08 CN disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-4609928-A LEUCO DYES, COLOR DEVELOPERS, BISHENOL, P-HYDROXYBENZOIC ACID ESTER, POROSITY, FILLERS RICOH COMPANY, LTD. (JP) 1986-09-02 US disclosed
US-4580152-A SHIFTING TRANSFER SHEET, CONTAINING LEUCO DYE, LATERALLY WITH RESPECT TO THERMAL HEAD RICOH CO., LTD. (JP) 1986-04-01 US disclosed
US-4538164-A LEUCO DYE, HYDROXYPHENOLIC ETHER DEVELOPER, OIL ABSORBING FILLER RICOH CO., LTD. (JP) 1985-08-27 US disclosed
EP-0016167-B1 POLYCARBONATE COMPOSITIONS HAVING IMPROVED BARRIER PROPERTIES GENERAL ELECTRIC COMPANY (US) 1984-09-26 EP disclosed
US-4307187-A THIOSULFONIC ACIDS PREVENT HEAT FOG WHEN STORED, REDUCING AGENTS FUJI PHOTO FILM CO., LTD. (JP) 1981-12-22 US disclosed
US-4258129-A IMPROVE GREEN SHELF LIFE FUJI PHOTO FILM CO., LTD. (JP) 1981-03-24 US disclosed
US-4211839-A SILVER HALIDE AND ORGANIC SILVER SALT PREPARED IN AN IMINO COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1980-07-08 US disclosed
US-4188212-A BEZNOTRIAZOLE FUJI PHOTO FILM CO., LTD. (JP) 1980-02-12 US disclosed
US-4002479-A ORGANIC SILVER SALT, SILVER HALIDE, AND A REDUCING AGENT FUJI PHOTO FILM CO., LTD. (JA) 1977-01-11 US disclosed
US-3991139-A NORBORNENE DERIVATIVES, PHENOLS, ESTER THIOETHERS SHOWA DENKO KABUSHIKI KAISHA (JA) 1976-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 ESR1 1265/4885ESR2 2595/4885AR 68/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.