Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6866367 | 0.89 | CX3CR1 (0.67) | CX3CR1CXCR2 | |
| SCHEMBL6866505 | 0.82 | CX3CR1 (0.69) | CX3CR1CXCR2 | |
| SCHEMBL215982 | 0.82 | CX3CR1 (0.80) | CX3CR1CXCR2 | |
| SCHEMBL215983 | 0.82 | CX3CR1 (0.80) | CX3CR1CXCR2 | |
| SCHEMBL6866114 | 0.82 | CXCR2 (0.65) | CX3CR1CXCR2 | |
| SCHEMBL5233299 | 0.81 | CX3CR1 (1.00) | CX3CR1CXCR2 | |
| SCHEMBL6869080 | 0.81 | CX3CR1 (0.79) | CX3CR1CXCR2 | |
| SCHEMBL5233311 | 0.81 | CX3CR1 (1.00) | CX3CR1CXCR2 | |
| SCHEMBL6869357 | 0.80 | CX3CR1 (0.76) | CX3CR1CXCR2 | |
| SCHEMBL5446092 | 0.80 | CX3CR1 (0.76) | CX3CR1CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6806273-B1 | 5-THIO-THIAZOLO(4,5-D)PYRIMIDIN-7-YL DERIVATIVES; CHEMOKINE RECEPTOR (ESPECIALLY CXCR2) ACTIVITY MODULATORS | ASTRAZENECA AB (SE) | 2004-10-19 | — | — | US | disclosed |