Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclooctanamine SCHEMBL6863778 | 1.00 | THRB (0.44) | THRBMEN1KMT2AALDH1A1MMP1 | |
| Cyclohexylamine SCHEMBL1679773 | 1.00 | — | — | |
| Methylamine SCHEMBL6865811 | 1.00 | THRB (0.44) | THRBMEN1KMT2AALDH1A1MMP1 | |
| Cyclopentanamine SCHEMBL6868657 | 0.96 | — | — | |
| Cyclohexylamine SCHEMBL8154944 | 0.92 | THRB (0.44) | THRBMEN1KMT2AALDH1A1MMP1 | |
| Cyclooctanamine SCHEMBL3037563 | 0.92 | THRB (0.44) | THRBMEN1KMT2AALDH1A1MMP1 | |
| SCHEMBL23379889 | 0.92 | THRB (0.50) | THRBMEN1KMT2AALDH1A1 | |
| SCHEMBL20858602 | 0.92 | THRB (0.50) | THRBMEN1KMT2AALDH1A1 | |
| SCHEMBL20830445 | 0.92 | THRB (0.50) | THRBMEN1KMT2AALDH1A1 | |
| SCHEMBL23379885 | 0.92 | THRB (0.50) | THRBMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6806289-B1 | SUCH AS AMMINE (2-AMINO-3-PICOLINE) DICHLOROPLATINUM(II); EFFICIENCY AND SELECTIVITY FOR DESTROYING TRANSFORMED CELLS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-10-19 | — | — | US | disclosed |