Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 3/20 | 0.32 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL14763033 | 0.86 | DPP8 (0.37) | HSD17B3NOTUMKMT2AMEN1MAPT | |
| SCHEMBL1301328 | 0.71 | NOTUM (0.44) | HSD17B3NOTUMRXFP1KMT2ANPC1 | |
| SCHEMBL14769042 | 0.70 | MAOA (0.46) | HSD17B3NOTUMRXFP1KMT2ANPC1 | |
| SCHEMBL16229965 | 0.68 | HSD17B3 (0.36) | HSD17B3NOTUMRXFP1KMT2AMEN1 | |
| SCHEMBL19812526 | 0.68 | NOTUM (0.35) | HSD17B3NOTUMKMT2ANPC1RAB9A | |
| SCHEMBL6866847 | 0.68 | HSD17B3 (0.37) | HSD17B3NOTUMRXFP1KMT2ANPC1 | |
| SCHEMBL25260022 | 0.67 | HSD17B3 (0.42) | HSD17B3NOTUMKMT2ANPC1RAB9A | |
| SCHEMBL11776394 | 0.65 | NOTUM (0.55) | HSD17B3NOTUMNPC1RAB9APOLB | |
| SCHEMBL13966515 | 0.64 | HSD17B3 (0.37) | HSD17B3NOTUMRXFP1KMT2ANPC1 | |
| SCHEMBL13976110 | 0.64 | NPC1 (0.39) | HSD17B3NOTUMKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194426-B1 | BENZOFURANE DERIVATIVES | MERCK PATENT GMBH (DE) | 2004-08-18 | — | — | EP | claimed |
| US-6531503-B1 | Central nervous system | MERCK PATENT GMBH (DE) | 2003-03-11 | — | — | US | claimed |
| EP-1194426-B1 | BENZOFURANE DERIVATIVES | MERCK PATENT GMBH (DE) | 2004-08-18 | — | — | EP | disclosed |
| US-6531503-B1 | Central nervous system | MERCK PATENT GMBH (DE) | 2003-03-11 | — | — | US | disclosed |