Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CDC25A | P30304 | 2/20 | 0.43 |
| ▸ | CDC25B | P30305 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30825761 | 0.90 | MAPT (0.40) | MAPTALDH1A1LMNAPOLBKDM4E | |
| SCHEMBL28890950 | 0.79 | ALDH1A1 (0.38) | MAPTALDH1A1LMNAPOLBCDC25B | |
| SCHEMBL7688765 | 0.76 | MAPT (0.43) | MAPTALDH1A1LMNAPOLBKDM4E | |
| SCHEMBL11176853 | 0.74 | CDC25A (0.33) | MAPTALDH1A1LMNAPOLBKDM4E | |
| SCHEMBL28728640 | 0.73 | MAPT (0.41) | MAPTALDH1A1LMNAPOLBKDM4E | |
| SCHEMBL9139763 | 0.72 | ATM (0.41) | MAPTALDH1A1LMNAPOLBTDP1 | |
| SCHEMBL29161382 | 0.72 | MAPT (0.54) | MAPTALDH1A1LMNAPOLBKDM4E | |
| SCHEMBL6299586 | 0.71 | MAPT (0.39) | MAPTALDH1A1LMNAPOLBKDM4E | |
| SCHEMBL6866011 | 0.71 | IDO1 (0.39) | MAPTALDH1A1LMNAPOLBKDM4E | |
| SCHEMBL28737069 | 0.71 | ATM (0.40) | MAPTALDH1A1LMNAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6809096-B1 | SUCH AS 11-METHOXY-7H-PYRIDO(4,3,2-DE)(1,7)PHENANTHROLINE-7-ONE; ANTITUMOR AGENTS | LABORATOIRE L. LAFON (FR) | 2004-10-26 | — | — | US | disclosed |