Propylene Oxide

Propylene Oxide

SCHEMBL6866878

CC1CO1.Nc1nc(N)nc(N)n1

nearest known ligand 0.39

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Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
CASP1 P29466 1/20 0.32
HTR2B P41595 1/20 0.31
PDE4D Q08499 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
HRH2 P25021 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31
NOS3 P29474 1/20 0.30
NOS1 P29475 1/20 0.30
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propylene Oxide SCHEMBL27553600 0.73
Propylene Oxide SCHEMBL27562381 0.73
Propylene Oxide SCHEMBL187161 0.73
Propylene Oxide SCHEMBL3957 0.73
Propylene Oxide SCHEMBL27304782 0.73 CHRM2 (0.39) LMNA
Propylene Oxide SCHEMBL65104 0.73
Propylene Oxide SCHEMBL2711413 0.73
Propylene Oxide SCHEMBL29630817 0.73
Propylene Oxide SCHEMBL1292008 0.73
Propylene Oxide SCHEMBL7628559 0.71 MAPT (0.47) LMNACASP1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6818726-B2 FOR INTERMEDIATES AND MOLDED MATERIALS WITH IMPROVED TOUGHNESS AND HIGH FLAME RESISTANCE AND STRENGTH AGROLINZ MELAMIN GMBH (AT) 2004-11-16 US disclosed
US-20030045667-A1 Polymers made from triazine derivatives AGROLINZ MELAMIN GMBH (AT) 2003-03-06 US disclosed