Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | GFER | P55789 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aniline SCHEMBL9226304 | 0.87 | TSHR (0.55) | MAPTKMT2AMEN1ALDH1A1TDP1 | |
| 4,4'-Methylenedianiline SCHEMBL7632512 | 0.86 | ALDH1A1 (0.61) | MAPTKMT2AMEN1ALDH1A1TDP1 | |
| Propylene Oxide SCHEMBL7623273 | 0.84 | ALDH1A1 (0.67) | MAPTKMT2AMEN1ALDH1A1TDP1 | |
| Aminobenzoic Acid SCHEMBL18092766 | 0.81 | TSHR (0.46) | MAPTALDH1A1TDP1CYP3A4TP53 | |
| Aminobenzoic Acid SCHEMBL367762 | 0.81 | TSHR (0.46) | MAPTALDH1A1TDP1CYP3A4TP53 | |
| Propylene Oxide SCHEMBL7628565 | 0.78 | CYP3A4 (0.53) | MAPTKMT2AMEN1ALDH1A1TDP1 | |
| Propylene Oxide SCHEMBL27562381 | 0.73 | — | — | |
| Propylene Oxide SCHEMBL27553600 | 0.73 | — | — | |
| Propylene Oxide SCHEMBL187161 | 0.73 | — | — | |
| Propylene Oxide SCHEMBL2711413 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724908-B1 | Process for hydrogenating an aromatic ring containing compound using a ruthenium Raney catalyst | SHOWA DENKO KK (JP) | 2002-04-24 | — | — | EP | disclosed |
| US-6245920-B1 | REACTING A 5-MEMBERED CYCLIC CARBOXYLIC ANHYDRIDE WITH HYDROGEN IN THE PRESENCE OF NOBLE METAL RANEY CATALYST TO REDUCE A CARBONYLOXY GROUP OF THE COMPOUND INTO A METHYLENEOXY GROUP TO CREATE A 5-MEMBERED LACTONE RING | SHOWA DENKO K.K. (JP) | 2001-06-12 | — | — | US | disclosed |
| US-6215030-B1 | CATALYTIC REDUCTION OF ACIDS, ESTERS AND ANHYDRIDES TO ALCOHOLS | SHOWA DENKO K.K. (JP) | 2001-04-10 | — | — | US | disclosed |
| US-6018048-A | PREPARING COMPOUNDS WITH HYDROGENATED RING STRUCTURE BY REACTING AN AROMATIC RING-CONTAINING COMPOUND WITH HYDROGEN IN THE PRESENCE OF A RANEY CATALYST COMPRISING AT LEAST 50% WEIGHT OF RUTHENIUM; MILDER TEMPERATURE, PRESSURE CONDITIONS | SHOWA DENKO K.K. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0934920-A2 | Preparation of hydrogenated compounds using noble metal Raney catalysts | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1999-08-11 | — | — | EP | disclosed |
| EP-0724908-A1 | Noble metal raney catalysts and preparation of hydrogenated compounds using such catalysts | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1996-08-07 | — | — | EP | disclosed |