⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12852246 | 1.00 | — | — | |
| SCHEMBL5943374 | 1.00 | — | — | |
| Cysteine SCHEMBL21747580 | 0.78 | PTGS1 (0.84) | — | |
| SCHEMBL17071957 | 0.78 | — | — | |
| SCHEMBL16704942 | 0.78 | — | — | |
| Cysteine SCHEMBL27613026 | 0.78 | PTGS1 (0.84) | — | |
| SCHEMBL11891014 | 0.78 | — | — | |
| SCHEMBL8583187 | 0.77 | — | — | |
| Cysteine SCHEMBL6244297 | 0.76 | PTGS1 (0.80) | — | |
| Cysteine SCHEMBL1275659 | 0.76 | PTGS1 (0.80) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0041935-B1 | N-(VINBLASTINOYL-23) DERIVATIVES OF AMINO ACIDS AND PEPTIDES AND THEIR PREPARATION | OMNICHEM Société anonyme (BE) | 1984-09-19 | — | — | EP | claimed |
| US-4388305-A | LESS TOXIC THAN VINCRISTINE OR VINDESINE | OMNICHEM S.A. (BE) | 1983-06-14 | — | — | US | claimed |
| US-20240067702-A1 | LACTAM-MODIFIED POLYPEPTIDE COMPOUNDS | TONGHUA DONGBAO PHARMACEUTICAL CO., LTD. (CN) | 2024-02-29 | — | — | US | disclosed |
| US-11746114-B2 | Thermally sensitive protecting groups for cysteine for peptide cyclization and selective disulfide bond formation | UNIVERSITY OF WINDSOR (CA) | 2023-09-05 | — | — | US | disclosed |
| US-11708513-B2 | Pressure sensitive adhesive comprising (meth)acrylic polymer and amino acid crosslinker | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-07-25 | — | — | US | disclosed |
| EP-3481383-B1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF IRRITABLE BOWEL SYNDROME | CELLIX BIO PRIVATE LTD (IN) | 2023-06-14 | — | — | EP | disclosed |
| WO-2023094680-A1 | PHOTODYNAMIC THERAPY AND DIAGNOSIS | RMW CHO GROUP LIMITED (CN) | 2023-06-01 | — | — | WO | disclosed |
| US-20230144876-A1 | IMMUNE INDUCER CONTAINING POLYNUCLEOTIDE-PEPTIDE CONJUGATE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | THE UNIVERSITY OF KITAKYUSHU (JP) | 2023-05-11 | — | — | US | disclosed |
| US-20230045048-A1 | IL-15 COMPOSITIONS AND METHODS OF USE THEREOF | PROVIVA THERAPEUTICS (HONG KONG) LIMITED (CN) | 2023-02-09 | — | — | US | disclosed |
| WO-2022174179-A9 | 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2023-02-02 | — | — | WO | disclosed |
| CN-114746105-A | IL-15 compositions and methods of use thereof | 普罗维瓦疗法香港有限公司 | 2022-07-12 | — | — | CN | disclosed |
| WO-2011017209-A1 | USE OF MELANOCORTINS TO TREAT DYSLIPIDEMIA | IPSEN PHARMA S.A.S. (FR) | 2011-02-10 | — | — | WO | disclosed |
| US-7785825-B2 | Compositions and methods for dehydration and cyclization of peptides, synthetic compounds, and lantibiotics | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2010-08-31 | — | — | US | disclosed |
| US-20100081786-A1 | Homogeneous Erythropoietin and Other Peptides and Proteins, Methods and Intermediates for Their Preparation | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-04-01 | — | — | US | disclosed |
| US-20090270457-A1 | 6,11-BICYCLOLIDES: BRIDGED BIARYL MACROLIDE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. | 2009-10-29 | — | — | US | disclosed |
| US-20090264380-A1 | 6,11-BRIDGED BIARYL MACROLIDES | ENANTA PHARMACEUTICALS, INC. | 2009-10-22 | — | — | US | disclosed |
| WO-2009061411-A2 | USE MELANOCORTINS TO TREAT INSULIN SENSITIVITY | IPSEN PHARMA S.A.S. (FR) | 2009-05-14 | — | — | WO | disclosed |
| US-20090118506-A1 | 6,11-BRIDGED BIARYL MACROLIDES | ENANTA PHARMACEUTICALS, INC. | 2009-05-07 | — | — | US | disclosed |
| US-20070082378-A1 | Convergent synthesis of proteins by kinetically controlled ligation | UNIVERSITY OF CHICAGO (US) | 2007-04-12 | — | — | US | disclosed |
| US-4388305-A | LESS TOXIC THAN VINCRISTINE OR VINDESINE | OMNICHEM S.A. (BE) | 1983-06-14 | — | — | US | disclosed |