⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27495390 | 0.78 | — | — | |
| SCHEMBL6866882 | 0.77 | — | — | |
| SCHEMBL5943374 | 0.77 | — | — | |
| SCHEMBL12852246 | 0.77 | — | — | |
| SCHEMBL20565756 | 0.76 | — | — | |
| SCHEMBL10641706 | 0.75 | SLC7A5 (0.43) | — | |
| SCHEMBL14227023 | 0.74 | NOS2 (0.38) | — | |
| SCHEMBL8101166 | 0.74 | NOS2 (0.38) | — | |
| SCHEMBL16659160 | 0.74 | NOS2 (0.38) | — | |
| SCHEMBL13287266 | 0.74 | NOS2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1192015-C | Cell adhesion inhibitors | BIOGEN INC (US) | 2005-03-09 | — | — | CN | claimed |
| CN-102391222-B | As the hydroxamic acid ester of therapeutical agent | PHARMACYCLICS INC. (US) | 2015-10-21 | — | — | CN | disclosed |
| CN-102482206-A | Polyfluorosulfonamido amides useful as intermediates in the synthesis of polyfluorosulfonamido amines | DU PONT | 2012-05-30 | — | — | CN | disclosed |
| CN-102391222-A | Novel hydroxamates as therapeutic agents | PHARMACYCLICS INC | 2012-03-28 | — | — | CN | disclosed |
| CN-102304110-A | Hydroxamates as therapeutic agents | AXYS PHARM INC | 2012-01-04 | — | — | CN | disclosed |
| CN-1768031-A | hydroxamates as therapeutic agents | AXYS PHARM INC (US) | 2006-05-03 | — | — | CN | disclosed |
| CN-1192015-C | Cell adhesion inhibitors | BIOGEN INC (US) | 2005-03-09 | — | — | CN | disclosed |
| US-5730903-A | LIQUID CRYSTALS | FUJI PHOTO FILM CO., LTD. (JP) | 1998-03-24 | — | — | US | disclosed |