Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.43 |
| ▸ | TAOK3 | Q9H2K8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5848731 | 1.00 | TAOK1 (0.43) | TAOK1TAOK3ALDH1A1DRD2POLB | |
| SCHEMBL5850513 | 1.00 | TAOK1 (0.43) | TAOK1TAOK3ALDH1A1DRD2POLB | |
| SCHEMBL5848493 | 1.00 | TAOK1 (0.43) | TAOK1TAOK3ALDH1A1DRD2POLB | |
| SCHEMBL5848743 | 1.00 | TAOK1 (0.43) | TAOK1TAOK3ALDH1A1DRD2POLB | |
| SCHEMBL5848769 | 0.96 | TAOK1 (0.49) | TAOK1TAOK3ALDH1A1DRD2POLB | |
| SCHEMBL5849933 | 0.94 | TAOK1 (0.41) | TAOK1TAOK3ALDH1A1DRD2POLB | |
| SCHEMBL5848335 | 0.94 | POLB (0.42) | TAOK1TAOK3ALDH1A1DRD2POLB | |
| SCHEMBL5850113 | 0.94 | CTSK (0.44) | TAOK1TAOK3ALDH1A1DRD2POLB | |
| SCHEMBL5848745 | 0.94 | TAOK1 (0.41) | TAOK1TAOK3ALDH1A1POLBHDAC1 | |
| SCHEMBL5848578 | 0.92 | TAOK1 (0.42) | TAOK1TAOK3ALDH1A1DRD2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6809092-B2 | 1,3,4,5-TETRAHYDRO-2H-2-BENZAZEPIN-2-YL DERIVATIVES; CYSTEINE PROTEASE INHIBITORS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-10-26 | — | — | US | claimed |