Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 7/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 7/20 | 0.50 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.44 |
| ▸ | MAP1LC3A | Q9H492 | 2/20 | 0.44 |
| ▸ | POLQ | O75417 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6867185 | 1.00 | KDM4E (0.51) | KDM4EALDH1A1MAPTHPGDHSP90AA1 | |
| SCHEMBL6864405 | 0.85 | KDM4E (0.42) | KDM4EALDH1A1MAPTHPGDHSP90AA1 | |
| SCHEMBL6864406 | 0.85 | KDM4E (0.42) | KDM4EALDH1A1MAPTHPGDHSP90AA1 | |
| SCHEMBL8444987 | 0.81 | HSP90AB1 (0.49) | KDM4EHSP90AA1HSP90AB1MAP1LC3BMAP1LC3A | |
| SCHEMBL6156108 | 0.81 | HSP90AB1 (0.49) | KDM4EHSP90AA1HSP90AB1MAP1LC3BMAP1LC3A | |
| SCHEMBL6867028 | 0.81 | HSP90AB1 (0.51) | KDM4EALDH1A1HPGDHSP90AA1HSP90AB1 | |
| SCHEMBL6866195 | 0.81 | HSP90AB1 (0.52) | KDM4EALDH1A1HPGDHSP90AA1HSP90AB1 | |
| SCHEMBL6867022 | 0.81 | HSP90AB1 (0.51) | KDM4EALDH1A1HPGDHSP90AA1HSP90AB1 | |
| SCHEMBL6866197 | 0.81 | HSP90AB1 (0.52) | KDM4EALDH1A1HPGDHSP90AA1HSP90AB1 | |
| SCHEMBL6938071 | 0.80 | HSP90AB1 (0.46) | KDM4EALDH1A1MAPTHPGDHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6812331-B2 | BACTERICIDES | AVENTIS PHARMA S.A. (FR) | 2004-11-02 | — | — | US | disclosed |
| US-6350733-B1 | 4-HYDROXYBENZOPYRAN-2-ONE DERIVATIVES; BACTERICIDES FOR STAPHYLOCOCCUS INFECTIONS; SKIN DISORDERS | AVENTIS PHARMA S.A. (FR) | 2002-02-26 | — | — | US | disclosed |
| US-20020010322-A1 | New aromatic derivatives substituted by a ribose, their preparation process and their use as medicaments | AVENTIS PHARMA S.A. | 2002-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020010322-A1 | New aromatic derivatives substituted by a ribose, their preparation process and their use as medicaments | RPIA, CD38, PARP1 | KDM4E 1566/4885ALDH1A1 1370/4885MAPT 3379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.