Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 8/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.41 |
| ▸ | MAP1LC3A | Q9H492 | 2/20 | 0.41 |
| ▸ | POLQ | O75417 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156108 | 1.00 | HSP90AB1 (0.49) | HSP90AB1HSP90AA1KMT2AMEN1LMNA | |
| SCHEMBL6156477 | 0.84 | HSP90AB1 (0.61) | HSP90AB1 | |
| SCHEMBL7743197 | 0.81 | HSP90AB1 (0.47) | HSP90AB1HSP90AA1KMT2AMEN1KDM4E | |
| SCHEMBL6867189 | 0.81 | KDM4E (0.51) | HSP90AB1HSP90AA1KMT2ALMNAKDM4E | |
| SCHEMBL6867185 | 0.81 | KDM4E (0.51) | HSP90AB1HSP90AA1KMT2ALMNAKDM4E | |
| SCHEMBL6938077 | 0.80 | HSP90AB1 (0.46) | HSP90AB1HSP90AA1KMT2AMEN1KDM4E | |
| SCHEMBL6938071 | 0.80 | HSP90AB1 (0.46) | HSP90AB1HSP90AA1KMT2AMEN1KDM4E | |
| SCHEMBL6156479 | 0.80 | HSP90AB1 (0.53) | HSP90AB1 | |
| SCHEMBL6160624 | 0.79 | HSP90AB1 (0.47) | HSP90AB1HSP90AA1KMT2ALMNAKDM4E | |
| SCHEMBL6157755 | 0.77 | HSP90AA1 (0.42) | HSP90AB1HSP90AA1KMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968939-A | ANTIBIOTICS FROM AMINOOXOBENZOPYRAN COMPOUNDS | HOECHST MARION ROUSSEL (FR) | 1999-10-19 | — | — | US | disclosed |