SCHEMBL6867384

SCHEMBL6867384

CCOC(=O)c1ccc(OCCO)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
KCNH2 Q12809 1/20 0.59
HRH3 Q9Y5N1 1/20 0.59
NR1I2 O75469 1/20 0.59
CA12 O43570 1/20 0.58
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
ESR1 P03372 1/20 0.58
CA7 P43166 1/20 0.58
CA9 Q16790 1/20 0.58
ESR2 Q92731 1/20 0.58
CA14 Q9ULX7 1/20 0.58
MAPT P10636 4/20 0.57
LMNA P02545 2/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
MAOA P21397 1/20 0.56
TBXAS1 P24557 1/20 0.56
GAA P10253 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3196742 0.97 KCNH2 (0.64) TDP1L3MBTL1KCNH2HRH3NR1I2
SCHEMBL6701399 0.91 TDP1 (0.74) TDP1L3MBTL1KCNH2HRH3CA12
SCHEMBL3966194 0.91 TDP1 (0.62) TDP1L3MBTL1KCNH2HRH3CA12
SCHEMBL18105961 0.91 TDP1 (0.62) TDP1L3MBTL1KCNH2HRH3CA12
SCHEMBL9109375 0.89 L3MBTL1 (0.59) TDP1L3MBTL1KCNH2HRH3CA12
SCHEMBL3626757 0.89 L3MBTL1 (0.59) TDP1L3MBTL1KCNH2HRH3CA12
SCHEMBL4536231 0.88 TDP1 (0.62) TDP1L3MBTL1KCNH2HRH3CA12
SCHEMBL8640140 0.88 KCNH2 (0.62) TDP1L3MBTL1KCNH2HRH3MAPT
SCHEMBL950916 0.88 L3MBTL1 (0.66) TDP1L3MBTL1KCNH2HRH3CA12
SCHEMBL5166263 0.88 TDP1 (0.66) TDP1L3MBTL1KCNH2HRH3CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116768914-A Fluorinated fluorescein derivative and preparation method thereof 中国原子能科学研究院 2023-09-19 CN disclosed
WO-2018138136-A1 PHARMACEUTICAL AGENT FOR IRON CHELATING Johannes Gutenberg-Universität Mainz (DE) 2018-08-02 WO disclosed
EP-1803773-B1 POLYMERIZABLE LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL FILM MADE FROM THE COMPOSITION NIPPON OIL CORP (JP) 2013-02-27 EP disclosed
US-7416765-B2 Polymerizable liquid crystalline composition and liquid crystal film made from the composition NIPPON OIL CORPORATION (JP) 2008-08-26 US disclosed
US-7416765-B2 Polymerizable liquid crystalline composition and liquid crystal film made from the composition NIPPON OIL CORPORATION (JP) 2008-08-26 US disclosed
US-20070164255-A1 POLYMERIZABLE LIQUID CRYSTALLINE COMPOSITION AND LIQUID CRYSTAL FILM MADE FROM THE COMPOSITION NIPPON OIL CORPORATION (JP) 2007-07-19 US disclosed
US-20070164255-A1 POLYMERIZABLE LIQUID CRYSTALLINE COMPOSITION AND LIQUID CRYSTAL FILM MADE FROM THE COMPOSITION NIPPON OIL CORPORATION (JP) 2007-07-19 US disclosed
EP-1803773-A1 POLYMERIZABLE LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL FILM MADE FROM THE COMPOSITION Nippon Oil Corporation (JP) 2007-07-04 EP disclosed
US-6805920-B2 For producing liquid crystal display (LCD) NITTO DENKO CORPORATION (JP) 2004-10-19 US disclosed
US-20030072893-A1 Polymerizable liquid crystal compound and optical film NITTO DENKO CORPORATION (JP) 2003-04-17 US disclosed
US-5955608-A Process for preparing benzoic acid derivative intermediates and benzothiophene pharmaceutical agents ELI LILLY AND COMPANY (US) 1999-09-21 US disclosed
EP-0530579-B1 Condensed pyrimidine derivatives antitumor agents EISAI CO LTD (JP) 1998-11-11 EP disclosed
EP-0699673-B1 Process for preparing benzoic acid derivative intermediates and benzothiophene pharmaceutical agents LILLY CO ELI (US) 1998-04-22 EP disclosed
US-5731436-A Process for preparing benzoic acid derivative intermediates and benzothiophene pharmaceutical agents ELI LILLY AND COMPANY (US) 1998-03-24 US disclosed
US-5688800-A ANTITUMOR AGENTS EISAI CO., LTD. (JP) 1997-11-18 US disclosed
CN-1143973-A Novel polymerisable liquid-crystalline compounds BASF AG (DE) 1997-02-26 CN disclosed
US-5554615-A ANTITUMOR EISAI CO., LTD. (JP) 1996-09-10 US disclosed
EP-0699673-A1 Process for preparing benzoic acid derivative intermediates and benzothiophene pharmaceutical agents ELI LILLY AND COMPANY (US) 1996-03-06 EP disclosed
EP-0530579-A1 Condensed pyrimidine derivatives antitumor agents Eisai Co., Ltd. (JP) 1993-03-10 EP disclosed