Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 9/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 7/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 5/20 | 0.46 |
| ▸ | HTR2B | P41595 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6867526 | 1.00 | MCHR1 (0.49) | MCHR1ADRA2AEPHX2NPC1RAB9A | |
| SCHEMBL6873496 | 0.94 | NPC1 (0.57) | MCHR1ADRA2AEPHX2NPC1RAB9A | |
| SCHEMBL6873499 | 0.94 | NPC1 (0.57) | MCHR1ADRA2AEPHX2NPC1RAB9A | |
| SCHEMBL6878062 | 0.92 | MEN1 (0.58) | MCHR1ADRA2AEPHX2NPC1RAB9A | |
| SCHEMBL6878058 | 0.92 | MEN1 (0.58) | MCHR1ADRA2AEPHX2NPC1RAB9A | |
| SCHEMBL6880492 | 0.90 | TP53 (0.45) | MCHR1ADRA2AEPHX2NPC1RAB9A | |
| SCHEMBL6880487 | 0.90 | TP53 (0.45) | MCHR1ADRA2AEPHX2NPC1RAB9A | |
| SCHEMBL6878317 | 0.90 | CCNC (0.53) | EPHX2SMN1; SMN2KMT2AMAPTMAPK1 | |
| SCHEMBL6878327 | 0.90 | CCNC (0.53) | EPHX2SMN1; SMN2KMT2AMAPTMAPK1 | |
| SCHEMBL6873659 | 0.90 | MCHR1 (0.51) | MCHR1ADRA2AEPHX2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |