Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | GHSR | Q92847 | 1/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.47 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6867574 | 1.00 | KMT2A (0.64) | KMT2ASMN1; SMN2USP2GHSRMAPK8 | |
| SCHEMBL6461553 | 0.91 | GHSR (0.61) | KMT2AGHSRMAPK8MAPK14TSHR | |
| SCHEMBL6461560 | 0.91 | GHSR (0.61) | KMT2AGHSRMAPK8MAPK14TSHR | |
| SCHEMBL6463041 | 0.88 | GHSR (0.55) | KMT2ASMN1; SMN2GHSRMAPK8MAPK14 | |
| SCHEMBL6463048 | 0.88 | GHSR (0.55) | KMT2ASMN1; SMN2GHSRMAPK8MAPK14 | |
| SCHEMBL13793334 | 0.82 | KMT2A (0.61) | KMT2AUSP2GHSRLMNAMAPT | |
| SCHEMBL6463319 | 0.81 | KMT2A (0.63) | KMT2AUSP2GHSRHTTLMNA | |
| SCHEMBL6472236 | 0.81 | KMT2A (0.63) | KMT2AUSP2GHSRHTTLMNA | |
| SCHEMBL6460655 | 0.78 | KMT2A (0.61) | KMT2ASMN1; SMN2USP2GHSRHTT | |
| SCHEMBL6460650 | 0.78 | KMT2A (0.61) | KMT2ASMN1; SMN2USP2GHSRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |